serum albumin is the most aboundant protein in blood plasma. its two major roles aremaintaining osmotic pressure and depositing and transporting compounds. in this paper,albumin-methanol solution simulation is carried out by three techniques including montecarlo (mc), molecular dynamic (md) and langevin dynamic (ld) simulations. byinvestigating energy changes by time and temperature (between 27...

Study of interaction between nicotinamide and human serum albumin using spectroscopic techniques molecular docking simulation

The interaction of long-chain fatty acids with cells is important for their uptake and metabolism, as well as their involvement in signalling processes. The majority of long-chain fatty acids circulating in plasma exist as complexes with serum albumin. Thus an understanding of the involvement of serum albumin in these processes is vitally important. The effect of serum albumin on the uptake of ...

BACKGROUND/AIM In randomised controlled trials (RCTs) of ursodeoxycholic acid (UDCA), although serum bilirubin is frequently reduced, its effect on disease progression and mortality is unclear. As serum albumin is an established independent prognostic marker, one might expect less deterioration of serum albumin values in a UDCA-treated group. We therefore modelled the typical evolution of serum...

Hundreds of proteins are dissolved in the plasma. By measuring the concentration of these proteins, the clinician can obtain information regarding disease states in different organ systems. The measurement of protein is done on serum, which is the fluid that remains after plasma has clotted, thus removing fibrinogen and most of the clotting factors. Total protein content provides some informati...

The lipid A component of bacterial lipopolysaccharides (endotoxins), when complexed to bovine serum albumin (BSA) or human serum albumin (HSA), was shown to be a potent pyrogen. Furthermore, rabbits could be protected against endotoxin fever by immunization with both lipid A BSA and lipid A HSA complexes. The results presented in this paper show that lipid A is responsible for the pyrogenic act...

Introduction:preeclampsia has remained one of the important obstetrical problems for which different factors have been suggested.decrease of serum levels of albumin,total protein and phosphorous have been suggested in the pathophysiology of precclampsia.the aim of this study was to determine serum levels of albumin,total protein and phosphorous in normal pregnancy and preeclamptic woman.   Me...

introduction: limited data are available on the relationship between nutritional status and tuberculosis. the aim of this study was to evaluate and compare the body mass index (bmi) and serum albumin level in patients with active tuberculosis (atb) and latent tuberculosis (ltb). materials and methods: a cross-sectional study was conducted on 17 patients newly diagnosed with pulmonary tb  who we...