Serologic monitoring is the way to determine adequate treatment response, which is typically defined as a fourfold decline in Rapid Plasma Reagin (RPR) or Veneral Disease Research Laboratory (VDRL) titer within 6 months of treatment for patients with primary or secondary syphilis and within 12 months of treatment for patients with early latent syphilis. Studies documented close to 100% rate ser...

background: celiac disease is one of the malabsorption syndromes leads to growth and development retardation in children. there is no test lonely can definitely diagnose celiac; however, the collection of clinical findings, serologic tests, intestinal biopsy, and response to treatment may diagnose it. although diagnostic value is variable in different studies, they are used a non-invasive and a...

Genomic analysis of the Chlamydiaceae has revealed a multigene family encoding large, putatively autotransported polymorphic membrane proteins (Pmps) with nine members in the sexually transmitted pathogen Chlamydia trachomatis. While various pathogenesis-related functions are emerging for the Pmps, observed genotypic and phenotypic variation among several chlamydial Pmps in various Chlamydia sp...

The global prevalence of hepatitis B virus is estimated to be 350 million chronic carriers, varying widely from low (<2%, as in Western Europe, North America, New Zealand, Australia, and Japan) to high (>8% as in Africa, Southeast Asia, and China). The overall prevalence in Brazil is about 8%. There are currently 7 genotypic variations, from A to G, and also 4 main surface antigen subtypes: adw...

BACKGROUND DNA-based methods are useful for enhancing immunohematology typings. Ready-to-use Conformité Européenne (CE)-marked test kits based on polymerase chain reaction with sequence-specific priming (PCR-SSP) have been developed, which enable the examination of weak, unexpected, or unclear serologic findings. DEVELOPMENT AND VALIDATION: Primers were designed according to established mutatio...

800x600 abstract: aim: the aim of this study was to investigate that the necessity of screening for celiac disease in idiopathic osteoporotic patients. background: osteopenia and osteoporosis are well-known and prevalent complications of celiac disease. however, the relative prevalence of celiac disease among osteoporotic populations is not known, and the benefit of screening for celiac disease...

We assessed the informativeness of several serologic biomarkers of immune function using serum specimens collected in the Miyazaki Cohort Study from subjects who were seronegative for anti-human T-cell lymphotrophic virus I and anti-hepatitis C virus. To broadly characterize type 1 immune status, we measured EBV antibody titers, because titer profiles associated with cellular immune suppression...

STUDY OBJECTIVE This study was designed to evaluate the usefulness of polymerase chain reaction (PCR) to detect Mycoplasma pneumoniae DNA in samples obtained by transthoracic needle aspiration (TNA). DESIGN Prospective study of cases. SETTING A university hospital in Lleida, Spain. PATIENTS A total of 101 unselected patients, admitted between January 1993 and March 1994 in the emergency d...

Detection of HIV-specific antibodies forms the corner stone for laboratory diagnosis of HIV infections. Serologic methods are routinely used to determine whether a host is infected with HIV, to evaluate the status of infections, and to assist monitoring antiretroviral therapy. Primary diagnosis of HIV infection is commonly accomplished by serology via detection of HIV antibody using a screening...