Abstract For quantitation of amlodipine (AML) and perindopril (PER) in their authentic, pharmaceutical formulations spiked human plasma, a simple, sensitive, validated inexpensive spectrofluorimetric method has been developed. The proposed is developed to be based on quantitative quenching effect two antihypertensive drugs Eosin Y's native fluorescence which was achieved by developing binary co...

fasting does have remarkable benefits in the treatment of cancer and another diseases such as metabolic syndrome, diabetes, and a multitude of other chronic diseases. it has been determined that fasting could play an important role during cancer treatment and progression via the regulation of insulin-like growth factor-1 (igf-1) as well as other growth factors. also, it has been shown that fast...

With the rapid progress of tissue engineering and regenerative medicine, the cell-friendly construction of a 3D extracellular matrix in a precisely controlled manner is needed. This biomimicry of the native extracellular matrix replicates major aspects of the native cellular microenvironment. Herein, we design a polyethylene glycol (PEG) based hydrogel combined with caging chemistry, which coul...

The evolution of tryptophan-to-heme (W/heme) distance distributions extracted from analysis of fluorescence energy transfer kinetics during the refolding of Rhodopseudomonas palustris cytochrome c' reveals dramatic differences between two variants [W32 (Q1A/F32W/W72F) and W72 (Q1A)]. Both W32/heme and W72/heme distance distributions measured at the earliest time point attainable with a continuo...