Hypersensitivity to para-phenylenediamine (PPD) and related compounds induced by temporary black henna tattoos has become a serious health problem worldwide. Different patterns of sensitization with various clinical aspects are described in literature due to PPD associated to henna tattoo and these manifestations are likely correlated with the immunological and dermatological pathomechanisms in...

Experience-dependent changes in behavior are thought to involve structural modifications in the nervous system, especially alterations in patterns of synaptic connectivity. Repeated experience with drugs of abuse can result in very long-lasting changes in behavior, including a persistent hypersensitivity (sensitization) to their psychomotor activating and rewarding effects. It was hypothesized,...

INTRODUCTION Much less is known about grass-pollen allergens to dogs, when compared with humans. Genetic-based patterns might play an important role in sensitization profiles, conditioning the success of allergen-specific immunotherapy. AIM Mapping of Dactylis glomerata (D. glomerata) and Phleum pratense (P. pratense) allergens for grass pollen-sensitized atopic dogs, for better understanding...

Rebekah Stevenson: Characterization of Adolescent and Adult Ethanol Sensitization (Under the direction of Dr. Clyde Hodge) Alcoholism is a serious health problem that affects the lives of millions of people worldwide. People that first experiment with alcohol as adolescents are at a greater risk to become alcoholics. The adolescent brain may be particularly vulnerable to druginduced neuroadapta...

background: atopic dermatitis is a major public health problem, often starting in early childhood and sometimes followed by other allergic diseases. although hypersensitivity to foods is assumed to play an essential role in the development of atopic dermatitis in some patients, little is known about common food allergens in iranian children with atopic dermatitis. objectives: this study was des...

BACKGROUND The gut microbiota is established during infancy and plays a fundamental role in shaping host immunity. Colonization patterns may influence the development of atopic disease, but existing evidence is limited and conflicting. OBJECTIVE To explore associations of infant gut microbiota and food sensitization. METHODS Food sensitization at 1 year was determined by skin prick testing ...

Even though nociceptive pathology has often long subsided, the brain of patients with chronic musculoskeletal pain has typically acquired a protective (movement-related) pain memory. Exercise therapy for patients with chronic musculoskeletal pain is often hampered by such pain memories. Here the authors explain how musculoskeletal therapists can alter pain memories in patients with chronic musc...

Background Lipid Transfer Proteins (LTP) and profilins are the most important panallergens in the clinical management of patients with allergy to pollen and plant food (mainly tree nuts and fresh fruits) in the Mediterranean countries. Knowledge of the prevalence of sensitization to these allergens in the population would be extremely useful. In this study we analyze the frequency of sensitizat...