According to the International Association for the Study of Pain (IASP) pain is characterized as an "unpleasant sensory and emotional experience associated with actual or potential tissue damage". The TRP super-family, compressing up to 28 isoforms in mammals, mediates a myriad of physiological and pathophysiological processes, pain among them. TRP channel might be constituted by similar or dif...

In t h i s paper we p r o v i d e a b r i e f d i s c u s s i o n o f t he r e l a t i o n s h i p o f t a c t i l e sensa t i on t o o the r sensory m o d a l i t i e s c u r r e n t l y showing prominence i n i n d u s t r i a l r o b o t s . A t a c t i l e sensor i s p resented which p r o v i d e s a m a t r i x o f t he f o r c e s e x i s t i n g between i t and the o b j e c t w i t h w...

We know from daily experiences that visual sensations persist for some time following any momentary stimulation of light to the retina,-a fact generally known as "after-image." After-images are classified into positive and negative, but little has hitherto been known about the exact time relation of these phenomena, because both the beginning and the end of sensations are difficult to be marked...

According to purists, visual experience can be exhaustively characterised in terms of a subject’s apparent perspective on external, public reality. Visual experience presents us (or if we are subject to illusion, apparently presents us) with aspects of the world beyond us—nothing more, nothing less. According to sensationalists, we cannot adequately characterise experience solely in terms of a ...

There are a number of serious shortcomings in the book. The title "Primer for the Psychotherapist" is quite misleading as this suggests that it contains an account of basic skills for psychotherapists but, in fact, it indicates that the non-medical psychotherapist should be able to differentiate between such conditions as duodenal ulcer, ulcerative colitis, Parkinson's disease and thyrotoxicosi...

In order to appreciate the clinical significance of this test it is necessary to understand the basic anatomy of the somatosensory pathways involved (see Figure 1). The afferent fibres arising from the cutaneous receptors responsible for the detection of vibration, together with those of touch and proprioception, synapse with the first order neurons located in the dorsal root ganglia of the spi...

Mechanosensing of surfaces in bacteria is a process that often uses obstruction of flagellum rotation to trigger behaviors such as adhesion and surface-associated movement. In a recent publication, the PilY1 protein of Pseudomonas aeruginosa has been implicated as a novel mechanosensor that stimulates virulence in response to surface attachment.

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Previous studies examining sex and age-related differences in sensation seeking havemainly focused on specific patterns of behaviour that can be described as a youthful behaviour style. In contrast, the present study assessed age and sex differences in sensation seeking using the need inventory of sensation seeking (NISS). This instrument measures sensation seeking without items which are descr...

Chile peppers are one of the most important vegetable and spice crops in the world. They contain capsaicinoids that are responsible for the characteristic burning (pungency) sensation. Currently, there are 22 known naturally occurring capsaicinoids that can cause the heat sensation when consumed. Each produces a different heat sensation effect in the mouth. A need exists for a standard and new ...