Aminopeptidases that generate antigenic peptides influence immunodominance and adaptive cytotoxic immune responses. The mechanisms that allow these enzymes to efficiently process a vast number of different long peptide substrates are poorly understood. In this work, we report the structure of insulin-regulated aminopeptidase, an enzyme that prepares antigenic epitopes for cross-presentation in ...

Abstract: Let be a commutative ring and be a unitary module. We define a semiprime submodule of a module and consider various properties of it. Also we define semi-radical of a submodule of a module and give a number of its properties. We define modules which satisfy the semi-radical formula and present the existence of such a module.  

In this paper, by using the sequence of adjointable operators from pro-C*-algebra $ mathcal{A} $ into a Hilbert $ mathcal{A} $-module $ E $. We introduce frames with bounds in pro-C*-algebra $ mathcal{A} $. New frames in Hilbert modules over pro-C*-algebras are called standard $ ast $-frames of multipliers. Meanwhile, we study several useful properties of standard $ ast $-frames in Hilbert modu...

Purpose. To assess the effect of three-dimensional (3D) printed personalized moisture chamber spectacles (PMCS) on the periocular humidity. Methods. Facial computed tomography (CT) scanning was conducted on 10 normal subjects. PMCS was designed based on volume rendered CT images and produced using a 3D printer. Periocular humidity of PMCS and commercially available uniformed moisture chamber sp...

Small round-structured viruses (SRSV) are a group of RNA viruses that can cause gastroenteritis in persons of all ages. To determine the incidence of SRSV-associated gastroenteritis in The Netherlands and to study the genetic variability of outbreak strains, all outbreaks that were reported to the epidemiologists of the regional health services in 1996 were investigated using a standardized pro...

Fresh gas flows of 1-5 l./min containing oxygen concentrations of 25-50% in nitrous oxide were led into a semiclosed circle absorber circuit. The resulting inspired oxygen concentrations were measured under conditions of spontaneous respiration. The lower the fresh gas flow, the greater was the discrepancy between fresh gas and inspired oxygen concentration. No association between minute volume...

The Heston model is appealing as it possesses a stochastic volatility term as well as semiclosed formulas for pricing European options. Unfortunately, few simulation schemes for this model can handle the violation of the Feller Condition. An algorithm based on the exact scheme of Broadie and Kaya to simulate price paths under the Heston model is introduced. In order to increase the speed of the...

In this paper, we define super Hilbert module and investigate frames in this space. Super Hilbert modules are  generalization of super Hilbert spaces in Hilbert C*-module setting. Also, we define frames in a super Hilbert module and characterize them by using of the concept of g-frames in a Hilbert C*-module. Finally, disjoint frames in Hilbert C*-modules are introduced and investigated.

Controlled frames have been introduced to improve the numerical efficiency of iterative algorithms for inverting the frame operator on abstract Hilbert spaces. Fusion frames and g-frames generalize frames. Hilbert C*-modules form a wide category between Hilbert spaces and Banach spaces. Hilbert C*-modules are generalizations of Hilbert spaces by allowing the inner product to take values in a C*...