It is well known that in general, an increased oxidative stress is found in cancer cells (e.g. [1, 2]). Low and high LET radiations induce reactive oxidative species and thus increase the oxidative stress even more. Different cancer cells not only do repair the DNA damage differently, they also cope differently with oxidative stress. Increasing the oxidative stress before irradiation might poss...

BACKGROUND Selenium and Tellurium have many common chemical properties as both belong to group 16 of the periodic table. High toxicities of Se and Te oxyanions cause environmental problems in contaminated soils and waters. Three strains (C4, C6 and C7) of selenite reducing and nanoparticle forming aerobic bacteria which were isolated from agricultural soils of India containing high concentratio...

Acute paraquat (PQ) toxicity induces redox cycling leading to fatality in both man and animals with clinical management being supportive therapy due lack of specific effective antidote. This study thus aimed at determining the sero-biochemical pathological changes induced by acute PQ administration male rats mitigating role sodium selenite. Forty were used for grouped into 5 eight viz: Group I ...

PURPOSE In this study, we investigated the biochemical pharmacology of pirenoxine (PRX) and catalin under in vitro selenite/calcium- and ultraviolet (UV)-induced lens protein turbidity challenges. The systemic effects of catalin were determined using a selenite-induced cataractogenesis rat model. METHODS In vitro cataractogenesis assay systems (including UVB/C photo-oxidation of lens crystall...

Newborn lambs depend on their dams for passive transfer of immunoglobulins, primarily IgG, for protection from harmful pathogens until their own immunological defenses have developed. Previous studies have suggested that supplementation with Se results in a modest increase in IgG concentration in serum of newborn calves and lambs. To evaluate the effect of the Se source and supplementation rate...

The bioavailability of Se from raw and cured selenomethionine-enriched (Se-enriched) salmon fillets was assessed in Se-deficient male albino rats (Mol: Wist). A low-Se Torula yeast feed was supplemented with 0, 50, 100, 150 or 200 microg Se/kg as sodium selenite or as Se from raw or cured Se-enriched salmon. The diets were fed to weanling rats for 10 and 30 d. Bioavailability of Se was assessed...

Selenium (Se) occurs in various forms in soils, including inorganic selenite and selenate and organic selenomethionine. Plant uptake of the inorganic, but not the organic forms, has been studied extensively. Organic-Se uptake was therefore examined in two-grooved milkvetch (Astragalus bisulcatus (Hook.) Gray), a Se-accumulating forb, and western wheatgrass (Pascopyrum (Rydb.) Love), a non-Se ac...

Intervention trials with different forms of selenium are under way to assess the effects of selenium supplements on the incidence of cancer and other diseases. Plasma selenium biomarkers respond to selenium administration and might be useful for assessing compliance and safety in these trials. The present study characterized the effects of selenium supplementation on plasma selenium biomarkers ...

Cataract is clouding of the eye lens that reduces the amount of incoming light and results in deteriorating vision. Blindness is thought to reach 75 million by 2020. Of these, unoperated cataract may be expected to account for at least 35 million. Thus, the burden of cataract is increasing remorselessly. Embelica officinalis is reported to have a very good antioxidant property and thus we hypot...

Concentrations of dissolved selenium (Se) as large as 330 pg L-' have been detected in water samples &om bacW aquifers in the southern Powder River Basin (PRB) of northeastern Wyoming. During d a c e coal mining, rock mstwial overiymg the coal is redistributed in relation to its original stratigraphic position; exposure of the prewiously buried material to surface oxidizing conditions decreases...