نتایج جستجو برای: selectivity index
تعداد نتایج: 440381 فیلتر نتایج به سال:
the bottom trawl selectivity parameters (22mm cod-end mesh size) were determined for saurida undosquamis , mullus barbatus , upeneus pori , and pagellus erythrinus along karatas coasts of turkey in northeastern mediterranean waters during fishing season for the year 2002-2003. the lengths at first capture (l 50 ) values for s. undosquamis , m. barbatus , u. pori and p. erythrinus were 12.57, 9....
In an attempt to identify potential new agents that are active against HIV-1, a series of novel pyridopyrimidine-5-carbohydrazide derivatives featuring a substituted benzylidene fragment were designed and synthesized based on the general pharmacophore of HIV-1 integrase inhibitors. The cytotoxicity profiles of these compounds showed no significant toxicity to human cells and they exhibited anti...
atp-sensitive potassium (katp) channel openers have a relaxation effect due to the lower cellular membrane potential and inhibit calcium influx. there has been considerable interest in exploring katp channel openers in the treatment of various diseases such as cardiovascular, cerebrovascular, and urinary system disease and premature labor. the purpose of this study was to synthesize 3,3,6,6-tet...
The effects of process variables (temperature, space velocity, water addition and Si/Al ratio) on the conversion of acetone to aromatic chemicals have been investigated. The reaction is carried out by fixed bed reactor at an atmospheric pressure to examine the activity and selectivity of HZSM-5. The results show that HZSM-5 exhibited a high active and a shape-selective catalyst for the formatio...
asymmetrically mixed matrix matrimid-mil-53 membranes with silicone cover layer were fabricated. for better understanding of membrane fabrication process, three main parameters of fabrication, matrimid concentration, silicone concentration and weight percentage of metal organic framework (mil-53) particles, were optimized by an experimental design method. cross-section sem images were used to s...
BACKGROUND Six plants from Thailand were evaluated for their cytotoxicity and apoptosis induction in human hepatocarcinoma (HepG2) as compared to normal African green monkey kidney epithelial cell lines. METHODS Ethanol-water crude extracts of the six plants were tested with neutral red assay for their cytotoxicity after 24 hours of exposure to the cells. Apoptotic induction was tested in the...
Oncolytic viruses are generally designed to be cancer selective on the basis of a single genetic mutation. JX-594 is a thymidine kinase (TK) gene-inactivated oncolytic vaccinia virus expressing granulocyte-macrophage colony-stimulating factor (GM-CSF) and lac-Z transgenes that is designed to destroy cancer cells through replication-dependent cell lysis and stimulation of antitumoral immunity. J...
Sediment selectivity during transport may provide basic information for evaluating on-site and off-site impacts of the soil erosion. Limited information is, however, available on the selectivity of sediments in rill erosion, particularly in the rainfed furrows. Toward this, the sediment selectivity was investigated in three soil textures (loam, loamy sand sand clay loam) under 10% slope using 9...
Paclitaxel (Taxol) is a chemotherapeutic agent that prevents disassembly of microtubular polymers, causing a growth arrest in the G2-M phase of the cell cycle and leading to apoptotic death. Paclitaxel has remarkable efficacy against fast-growing tumors but possesses major drawbacks, such as poor solubility and lack of tumor selectivity. Conversely, monoclonal antibodies usually have low therap...
Bispecific antibodies are considered attractive bio-therapeutic agents owing to their ability to target two distinct disease mediators. Cross-arm avidity targeting of antigen double-positive cancer cells over single-positive normal tissue is believed to enhance the therapeutic efficacy, restrict major escape mechanisms and increase tumor-targeting selectivity, leading to reduced systemic toxici...
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