نتایج جستجو برای: sebaceous differentiation

تعداد نتایج: 230160  

2016
Paul M Graham Stephen W Eubanks

Background: Sebaceous hyperplasia is a benign but clinically and cosmetically unappealing lesion. Historical treatments include cauterization, cryotherapy, chemical ablation, and surgical removal, all of which increase the risk for permanent post-operative adverse effects. The pulsed-dye laser (PDL) offers a safe and effective approach to the treatment of sebaceous hyperplasia in Fitzpatrick sk...

MJ Nazemi S Toosi SN Emadi

Cyclosporin and azathioprine are immunosuppressive drugs, used widely in kidney transplant patients. A significant association between immunosuppressive therapy and multiple warts was described several years ago. There are also some reports of sebaceous gland hyperplasia in kidney transplant patients receiving cyclosporin. We report herein a 57-year-old woman who developed multiple warts on her...

2008
K. A. TERİM KAPAKİN F. BOZKURT R. HAZIROĞLU

Terim Kapakin K.A., F. Bozkurt, R. Haziroğlu: Sebaceous Adenocarcinoma in a Cat. Acta Vet. Brno 2008, 77: 123-125. In this study, the sebaceous gland adenocarcinoma was presented in the external auditory canal of a 10-year-old female tabby cat. There were three tumoural masses located macroscopically in the external auditory canal in the dimensions of 0.2 × 0.5, 0.3 × 0.5, and 0.1 × 0.1 cm, and...

2017
Mingang Xu Jeremy Horrell Melinda Snitow Jiawei Cui Heather Gochnauer Camille M Syrett Staci Kallish John T Seykora Fei Liu Dany Gaillard Jonathan P Katz Klaus H Kaestner Brooke Levin Corinne Mansfield Jennifer E Douglas Beverly J Cowart Michael Tordoff Fang Liu Xuming Zhu Linda A Barlow Adam I Rubin John A McGrath Edward E Morrisey Emily Y Chu Sarah E Millar

Human WNT10A mutations are associated with developmental tooth abnormalities and adolescent onset of a broad range of ectodermal defects. Here we show that β-catenin pathway activity and adult epithelial progenitor proliferation are reduced in the absence of WNT10A, and identify Wnt-active self-renewing stem cells in affected tissues including hair follicles, sebaceous glands, taste buds, nails...

Journal: :Trends in pharmacological sciences 2009
Tamás Bíró Balázs I Tóth György Haskó Ralf Paus Pál Pacher

The newly discovered endocannabinoid system (ECS; comprising the endogenous lipid mediators endocannabinoids present in virtually all tissues, their G-protein-coupled cannabinoid receptors, biosynthetic pathways and metabolizing enzymes) has been implicated in multiple regulatory functions both in health and disease. Recent studies have intriguingly suggested the existence of a functional ECS i...

2013
Carla Kellen da Silva Menezes Nathália Matos Gomes Alex Panizza Jalkh Emily dos Santos Franco Thalita Gomes Martins

Sebaceous adenocarcinoma is a rare adnexal tumor that can affect the skin and is divided into ocular, a more common form and extra ocular, of a rarer occurrence. We report the case of a patient diagnosed with Acquired Immune Deficiency Syndrome (AIDS) who developed an extra ocular, bulky and fast-growing sebaceous adenocarcinoma on the face. The literature has suggested that transplanted patien...

Journal: :Head & neck 2012
Geir Tryggvason Rodrigo Bayon Nitin A Pagedar

BACKGROUND The purpose of this study was to describe the incidence of nodal disease in sebaceous carcinoma and its impact on survival. METHODS Data from the 17 registries of the Surveillance, Epidemiology, and End Results (SEER) database was retrospectively collected for sebaceous carcinoma from 1973 to 2007. Information on location, histologic grade, stage of disease, and survival was gather...

Journal: :Cancer research 1956
A A KANDUTSCH E D MURPHY M E DREISBACH

The sterol A7-cholestenol constitutes a large proportion of the total sterols of rat and mouse skin (5, 7, 18). Whereas the concentration of this sterol is not altered by such factors as diet, metabolic rate (7), and ultraviolet light (13), it decreases rapidly following the application of carcinogenic hydrocarbons to mouse skin (5). This decrease coincides with destruction of the sebaceous gla...

2015
Dilip Y Paithankar Fernanda H Sakamoto William A Farinelli Garuna Kositratna Richard D Blomgren Todd J Meyer Linda J Faupel Arielle N B Kauvar Jenifer R Lloyd Wang L Cheung Witold D Owczarek Anna M Suwalska Katarzyna B Kochanska Agnieszka K Nawrocka Elwira B Paluchowska Katarzyna M Podolec Magdalena M Pirowska Anna B Wojas-Pelc R Rox Anderson

The pathophysiology of acne vulgaris depends on active sebaceous glands, implying that selective destruction of sebaceous glands could be an effective treatment. We hypothesized that light-absorbing microparticles could be delivered into sebaceous glands, enabling local injury by optical pulses. A suspension of topically applied gold-coated silica microparticles exhibiting plasmon resonance wit...

2016
D.L. Cottle K. Kretzschmar H.P. Gollnick S.R. Quist

DEAR EDITOR, Skin diseases affect a significant percentage of the population and are often the result of a complex interplay between autoimmune dysregulation, and abnormal epidermal differentiation and proliferation. Origins may be genetic and/ or environmental, and while no complete cure exists for conditions such as psoriasis, a range of treatments, including reti-noids and antibodies against...

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