BACKGROUND A randomized trial was performed to assess the effect of spinal cord stimulation (SCS) on detection and pain thresholds for pressure, warmth, and cold and on the extent of mechanical hyperalgesia in patients with chronic complex regional pain syndrome type I. METHODS Fifty-four chronic complex regional pain syndrome type I patients were randomized to receive both SCS and physical t...

Spinal cord stimulation (SCS) is a therapy used to treat intractable pain with a putative mechanism of action based on the Gate Control Theory. We hypothesized that sensory projection neuron responses to SCS would follow a single stereotyped response curve as a function of SCS frequency, as predicted by the Gate Control circuit. We recorded the responses of antidromically identified sensory pro...

the aim of this study was using bayesian approach via gibbs sampling (gs) for estimating genetic parameters of production, reproduction and health traits in iranian holstein cows. data consisted of 320666 first- lactation records of holstein cows from 7696 sires and 260302 dams collected by the animal breeding center of iran from year 1991 to 2010. (co) variance components were estimated using ...

We showed previously that bacterially expressed full-length human wild-type p53b(1-393) binds selectively to supercoiled (sc)DNA in sc/linear DNA competition experiments, a process we termed supercoil-selective (SCS) binding. Using p53 deletion mutants and pBluescript scDNA (lacking the p53 recognition sequence) at native superhelix density we demonstrate here that the p53 C-terminal domain (am...

Previously, it has been shown that rat Schwann cells (SCs), but not olfactory ensheathing cells (OECs), form a boundary with astrocytes, due to a SC-specific secreted factor. Here, we identify highly sulfated heparan sulfates (HSs) and fibroblast growth factors (FGFs) 1 and 9 as possible determinants of boundary formation induced by rat SCs. Disaccharide analysis of HS in SC-conditioned and rat...

Muscle satellite cells (SCs) are stem cells that reside in skeletal muscles and contribute to regeneration upon muscle injury. SCs arise from skeletal muscle progenitors expressing transcription factors Pax3 and/or Pax7 during embryogenesis in mice. However, it is unclear whether these fetal progenitors possess regenerative ability when transplanted in adult muscle. Here we address this questio...

BACKGROUND The peritoneal carcinomatosis index (PCI) can be used to quantify the tumor burden in patients with advanced ovarian cancer. The aim of the present study was to establish a predictive model for suboptimal cytoreductive surgery (SCS) (residual tumor of > 1 cm) using preoperative and intraoperative determination of the PCI. METHODS In total, 110 consecutive patients treated for advan...

The semicircular canal (SC) system of the inner ear detects head angular accelerations and is essential for navigation and spatial awareness in vertebrates. Because the bony labyrinth encloses the membranous labyrinth SCs, it can be used as a proxy for animal behavior. The bony labyrinth of dicynodonts, a clade of herbivorous non-mammalian synapsids, has only been described in a handful of indi...

Stem cells (SCs) are undifferentiated cells capable of self-renewal and differentiation into multiple functional cell types. These cells are widely used in injury repair and tissue regeneration.1,2 Adult SCs have been isolated from a variety of tissues including bone marrow, brain, liver, lungs, breast, skin, skeletal muscles, hair follicles and teeth.3,4 Dental-derived SCs have been isolated a...

In this study test-day records of milk (kg), fat (g), and protein (g) yields, somatic cell score (SCS, cells/ML) collected by Animal Breeding Center of Iran during 2007 and 2009 were used to estimate genetic parameters using random regression model. Models with different order of Legendre polynomials were compared using Bayesian information criterion (BIC).For milk, fat yield and SCS genetic an...