Schizophrenia is a complex disorder with polygenic inheritance. The MTHFR gene (OMIM: 607093) plays an important role in the folate metabolism. It has been suggested that C677T (rs1801133) and A1298C (rs1801131) genetic polymorphisms in the MTHFR gene lead to the decreased activity of the methylenetetrahydrofolate reductase enzyme which may have significant effect on developing schizophrenia. W...

Introduction: This study aims to compare the positive and negative symptoms of schizophrenia in patients who had psychotic symptoms more than one month after discontinuation of methamphetamine abuse. These factors were analyzed by the PANSS (Positive and Negative Syndrome Scale) questionnaire. Materials and Methods: 60 participants were selected from patients referred to Iran Psychiatric Hospi...

Abstract Drug trials for negative symptoms in schizophrenia select patients based on the severity and stability of symptoms, using criteria that are not suitable acute exacerbation schizophrenia. Here we present a method to prognostically enrich subjects having predefined factor structure PANSS apply it measurement specifically A vector 1335 elements between- within-item variances, covariances,...

Schizophrenia is a chronic psychoneurological condition that encompasses wide variety of neurochemical, morphological, bioelectrical and behavioural changes. Comprehension the mechanisms underlying schizophrenia psychosis cannot be fully acquired in clinical studies with humans. For this reason, number experimental animal models have been developed. Although none existing reproduces complete sp...

Schizophrenia is a major mental illness with children of affected individuals experiencing multiple challenges, which are often overlooked by professionals. These at risk health issues due to reasons including genetic predisposition, poor attachment in relationships and chaotic family environments. We describe an unusual presentation child whose mother was suffering from schizophrenia.

objective: despite the discovery of new antipsychotic drugs in recent years, a number of schizophrenic patients show no response to such drugs and are considered treatment-resistant. in such cases, clozapine and occasionally ect or a combination of drugs are used, though they are not very effective. in recent years, the combination of clozapine and ect for treatment-resistant schizophrenic pati...

conclusions it can be concluded that schizophrenia can have an effect on the quality of life. some items such as family care, early and on time treatment play an important role in increasing the quality of life. results the participants in this study gained the highest quality of life in the domain of physical, environmental and psychological health and social relationships. there was no signif...

conclusions after eight sessions, increased awareness of the environment, improved posture and gait pattern, improved motivation and enjoyment, improved patient tolerance, improved appearance and personal hygiene, loss of purposeful behavior, a realistic plan of action every day, improved attention span, improved decision-making skills, and improved community involvement and coping skills were ...

ôbjective: recently, quality of life is a concern of health in psychiatry. schizophrenia is a disorder that has the most regressive effects in societies’ and patients’ behavioural, occupational and psychiatric aspects. the main purpose of this study was to evaluate the quality of life and global function of schizophrenia patients. methods: â hundred schizophrenia patients (with dsm-ïv-tr) who h...