Bayley Raiz: The authors’ discussion of the functional disconnect between a patient’s attitude in treatment and behavior outside resonates with my own clinical experience. We regularly see patients who sincerely and intensely desire to quit abusing substances, but cannot yet “walk the walk” of recovery. This deserves all the emphasis the authors give it. Clinicians sometimes think that patients...

A conceptual analysis of modelling is undertaken. The major challenges posed by the growth of open and integrated systems prompts a careful rethinking of the basis of modelling. Particular attention is paid to object-oriented modelling. Our approach is characterized by an analytic framework borrowed from the philosophy of language called theories of reference (ToRs). This body of theories aims ...

Adenosine-to-inosine (A-to-I) editing has been shown to be an important mechanism that increases protein diversity in the brain of organisms from human to fly. The family of ADAR enzymes converts some adenosines of RNA duplexes to inosines through hydrolytic deamination. The adenosine recognition mechanism is still largely unknown. Here, to investigate it, we analyzed a set of selectively edite...

The accuracy of height predictions at various ages based on five different methods (Tanner-Whitehouse mark I; Tanner-Whitehouse mark II; index of potential height; Bayley-Pinneau; Roche-Wainer-Thissen) was compared at yearly intervals with final height achieved in 32 boys (78 predictions) and 100 girls (227 predictions) with constitutionally tall stature. The boys were initially seen at a mean ...

Individuals with autism spectrum disorders (ASD) and complex communication needs often rely on augmentative and alternative communication (AAC) as a means of functional communication. This meta-analysis investigated how individual characteristics moderate effectiveness of three types of aided AAC: the Picture Exchange Communication System (PECS), speech-generating devices (SGDs), and other pict...

Bu çalışmada ortaokul öğrencilerinin sosyal katılım becerilerini belirleyebilmek için yeni bir ölçek geliştirilmiştir. Araştırma sürecinde öncelikli olarak 90 maddelik madde havuzu oluşturulmuştur. Belirlenen maddeler alan uzmanlarının görüşleri doğrultusunda gözden geçirilmiş, kapsam geçerliği sağlanmaya çalışılmıştır. Düzeltmelerden sonra elde edilen taslak ölçek, 2021-2022 öğretim yılının ik...