This study focuses on determining the relationship between parents' step count (SC) and screen time (ST) and children's SC and ST on weekdays and at weekends. The participants (278 parents aged 30-45 and their 194 children aged 4-7) were recruited from 10 randomly selected Czech kindergartens. The participants recorded SC and ST duration over a week-long monitoring (≥8 h/day) during September-O...

Carbon-layered double hydroxide nanocomposite with surface area 758–477 m2 g−1 shows efficient removal of As(v), F−, Fe(ii)/Fe(iii), MB and MO.

Objectives To assess whether quantitative spinal cord MRI (SC-MRI) measures, including atrophy, and diffusion tensor imaging (DTI) and magnetization transfer imaging metrics were different in radiologically isolated syndrome (RIS) vs healthy controls (HCs). Methods Twenty-four participants with RIS and 14 HCs underwent cervical SC-MRI on a 3T magnet. Manually segmented regions of interest cir...

OBJECTIVES To evaluate the long-term efficacy and safety of subcutaneous (SC) tocilizumab (TCZ) versus intravenous (IV) TCZ, including switching formulations, in patients with rheumatoid arthritis (RA) and inadequate response to disease-modifying antirheumatic drugs (DMARDs). METHODS Patients (n=1262) were randomised 1:1 to receive TCZ-SC 162 mg weekly (qw)+placebo-IV every four weeks (q4w) o...

The synaptonemal complex (SC) is a widely conserved structure that mediates the intimate alignment of homologous chromosomes during meiotic prophase and is required for proper homolog segregation at meiosis I. However, fundamental details of SC architecture and assembly remain poorly understood. The coiled-coil protein, Zip1, is the only component whose arrangement within the mature SC of buddi...

The proposed paper gives a brief survey of situational control (SC) of complex systems development, also a brief survey of applications that were realized in the past period (SC of robotic technological complexes, SC of electric network, SC in metallurgy, SC in biomedicine, situational modeling, situational classification in projecting, etc.) The paper also deals with problems of decision – mak...

Consider a multi-channel supply chain (hereafter SC) system, producing and distributing two substitutable products. Within this framework, we study the SC efficiency by comparing several decentralized SC configurations with a centralized one. Our result show that it is often possible to achieve 93.5% or more of the total profit of a centralized SC in a decentralized configuration, which suggest...

social capital (sc) is important as much as physical capital and theorists discussed its functions in enhancement of countries. successfulness in international fields is far behind reach without due attention to capacity of countries. these capacities are known as competitiveness capacity (cc) in political literature. twelve indexes have been recognized for the cc which covers different dimensi...

The concept of in-air output ratio (Sc) was introduced to characterize how the incident photon fluence per monitor unit (or unit time for a Co-60 unit) varies with collimator settings. However, there has been much confusion regarding the measurement technique to be used that has prevented the accurate and consistent determination of Sc. The main thrust of the report is to devise a theoretical a...

Obatoclax is a small molecule which targets the Bcl-2 family, and is to treat leukemia, lymphoma and lung carcinoma. Previously, an obatoclax analogue, SC-2001, was found to disrupt the protein-protein interactions of the Bcl-2 family and also repress Bcl-XL and Mcl-1 expression via STAT3 inactivation. Here, we report a novel mechanism of autophagy induction by SC-2001 in liver cancer cells. Th...