Using simulation-based inference (SBI), such as randomization tests, the primary vehicle for introducing students to logic and scope of statistical has been advocated with potential improving student understanding investigative process a whole. Moving beyond individual class activity, entirely revised introductory statistics curricula centering on these ideas have developed tested. Preliminary ...

Social Business Intelligence (SBI) relies on user-generated content to let decision-makers analyze their business in the light of the environmental trends. SBI projects come in a variety of shapes, with different demands. Hence, finding the right cost-benefit compromise depending on the project goals and time horizon and on the available resources may be hard for the designer. In this paper we ...

Alcohol is strongly linked to the leading causes of adolescent and adult mortality and health problems, making medical settings such as primary care and emergency departments important venues for addressing alcohol use. Extensive research evidence supports the effectiveness of alcohol screening and brief interventions (SBIs) in medical settings, but this valuable strategy remains underused, wit...

Screening and brief intervention (SBI) as a method within secondary prevention of alcohol use-related problems has experienced enormous attention and interest over the past 20 years. Initial results were very promising and great effort was put into designing screening instruments and developing different kinds of interventions. However, at the same time, the approach has generated problems in i...

No randomized controlled trials (RCTs) of screening and brief intervention (SBI) have been conducted in the community pharmacy setting. This pilot study was designed to inform the development and implementation of a large-scale RCT. The study examined the feasibility of providing SBI in community pharmacies, including practical considerations, recruitment of pharmacists and clients, uptake, pot...

AIM To compare diagnostic accuracy of procalcitonin for early diagnosis of serious bacterial infection (SBI) in children presenting with fever and no focus of infection. METHODS Prospective, observational study involving 72 children (1-36 mo) presenting to the paediatric units of two university hospitals. All children had blood cultures, urine cultures, white blood cell counts (WBC), chest X-...

OBJECTIVE History and physical examination do not reliably exclude serious bacterial infections (SBIs) in infants. We examined potential markers of SBI in young febrile infants. DESIGN We reviewed white cell count (WBC), absolute neutrophil count (ANC), neutrophil to lymphocyte count ratio (NLR) and C reactive protein (CRP) in infants aged 1 week to 90 days, admitted for fever to one medical ...

We report on silent brain infarction (SBI) and leukoaraiosis (LA) of 23 patients with clinically diagnosed “first-ever” acute ischemic lacunar stroke. The lacunar syndromes were pure motor hemiparesis (10), pure sensory syndrome (2), ataxic hemiparesis (3), dysarthria clumsy hand syndrome (3), and sensorymotor deficit (5). Nineteen out of the 23 patients presented with completed strokes on arri...

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is particularly troublesome for pediatric patients, as current therapeutic options consist of biologic agents and steroids which alter the immune response and have the harmful side effect of leaving the patient more susceptible to opportunistic infections and eventual surgery. Another option for therapy exists in the form of s...

Stroke is the second leading cause of death in the world and in South Korea. Ischemic stroke and silent brain infarction (SBI) are complex, multifactorial diseases influenced by multiple genetic and environmental factors. Moderately elevated plasma homocysteine levels are a major risk factor for vascular diseases, including stroke and SBI. Folate and vitamin B12 are important regulators of homo...