The activation of cardiovascular reflexes for postural adaptation questions whether, in healthy humans, the central blood volume is optimised to support the upright position. A functional definition of an 'optimal circulating volume' that provides the heart with enough central blood volume to establish a maximal cardiac output (CO) and mixed venous oxygen saturation (S(v,O2)) at rest was evalua...

Metastatic dissemination of tumor cells is the most destructive complication in cancer diseases. During metastasis, tumor cells invade the blood, interact with blood components like platelets and leukocytes, arrest at the endothelial surface of distant organs, and finally transmigrate through the endothelium to proliferate in the tissue matrix. Since adhesion receptors are crucially involved in...

We develop and test a theory for the relationship of atmospheric pCO2 and the solubility pump of CO2 in an abiotic ocean. The solubility pump depends on the hydrographic structure of the ocean and the degree of saturation of the waters. The depth of thermocline sets the relative volume of warm and cold waters, which sets the mean solubility of CO2 in the ocean. The degree of saturation depends ...

AIM To determine if oxygen saturation in retinal vessels depends on the degree of diabetic retinopathy. MATERIAL AND METHODS A prospective study comparing values of oxygen saturation in retinal arteries, veins, and arterio - venous (A-V) difference in healthy persons and in patients with diagnosed diabetes. The study included 114 eyes of 76 patients with diagnosed diabetes, and 57 eyes of 57 ...

Seismic velocities in rocks at ultrasonic frequencies depend not only on the degree of saturation but also on the distribution of the fluid phase at various scales within the pore space. Two scales of saturation heterogeneity are important: (1) saturation differences between thin compliant pores and larger stiffer pores, and (2) differences between saturated patches and undersaturated patches a...

The prevalence of cholesterol gall stones in young women has increased since the introduction of oral contraceptives. The synthetic female sex hormones used in these preparations, increase the degree of cholesterol saturation in bile. To determine whether oestrogens, progestagens, or both, are responsible for the change in biliary cholesterol saturation index, a prospective randomised, controll...

The prevalence of cholesterol gall stones in young women has increased since the introduction of oral contraceptives. The synthetic female sex hormones used in these preparations, increase the degree of cholesterol saturation in bile. To determine whether oestrogens, progestagens, or both, are responsible for the change in biliary cholesterol saturation index, a prospective randomised, controll...

Two studies were designed to compare the effects on post-ingestive satiety of manipulating the degree of saturation of fatty acids, at a fixed chain length (18 C atoms), in a fixed energy (5.68 MJ for males; 3.97 MJ for females), high-fat (55% energy) lunch meal. Two different groups of twenty subjects (ten males and ten females) took part in each study. All forty subjects were of normal weight...

In engineering applications involving mechanics of geomaterials, focus is generally put on the deformation of the solid skeleton so that a great interest is given to the definition of the stresses governing the skeleton deformation. The presence of one or several fluids within the porous space of these materials introduces a complexity in the choice of the stress state variables with respect to...