PURPOSE To evaluate the efficacy of mesenchymal stem cells (MSCs) encapsulated in self-assembled peptide (SAP) hydrogels in a rat knee model for the prevention of osteoarthritis (OA) progression. MATERIALS AND METHODS Nanostructured KLD-12 SAPs were used as the injectable hydrogels. Thirty-three Sprague Dawley rats were used for the OA model. Ten rats were used for the evaluation of biotin-ta...

Ab is a crucial component of protective immunity to infection, but Ab responses do not proceed normally when defects occur in a protein called signaling lymphocytic activation molecule-associated protein (SAP). To explain this Ab defect, we analyzed B cell and plasma cell responses under conditions of SAP deficiency. Our results demonstrate that SAP-deficient (SAP knockout (KO)) mice have a pro...

Presence of autoantibodies precedes development of seropositive rheumatoid arthritis (SP RA) and seropositive arthralgia patients (SAP) are at risk of developing RA. The aims of the study are to identify additional serum immune markers discriminating between SP and seronegative (SN) RA, and markers identifying high-risk SAP. Sera from SAP (n = 27), SP RA (n = 22), SN RA (n = 11) and healthy con...

Activated mononuclear cells are an early event in the course of severe acute pancreatitis (SAP). To date, the molecular mechanism triggering peripheral blood mononuclear cells (PBMCs) is poorly understood. The aim of this paper was to determine the potential role of Card9 in SAP. We collected data from 72 subjects between January 2013 and June 2014. Subsequently, PBMCs were isolated on day 1, 3...

Fusional languages have rich inflection. As a consequence, tagsets capturing their morphological features are necessarily large. A natural way to make a tagset manageable is to use a structured system. In this paper, we present a positional tagset for describing morphological properties of Russian. The tagset was inspired by the Czech positional system (Hajič, 2004). We have used preliminary ve...

SAP is a well-established leader in the packaged applications market. The term packaged application typically refers to upscale enterprise software suites, such as ERP or CRM. In most cases, organizations that adopt SAP software remain heterogeneous enterprises. In heterogeneous enterprises, most SAP implementations must be integrated with various non-SAP enterprise systems, portals, messaging ...

Early intensive care for severe acute pancreatitis is essential for improving SAP mortality rates. However, intensive therapies for SAP are often delayed because there is no ideal way to accurately evaluate severity in the early stages. Currently, perfusion CT has been shown useful to predict prognosis of SAP in the early stage. In this presented paper, we would like to review the clinical usef...

The response of excised stem segments of several tree species to freezing and thawing cycles was studied. All species studied (Thuja occidentalis, Fagus grandifolia, and Betula papyrifera) except maple (Acer spp.) exuded sap while freezing and absorbed on thawing. Maple stems absorbed sap while freezing and exuded sap during the thaw only when sucrose was present in the vessel solution. Increas...

abstract to resist lateral loads in concrete buildings, usually systems such as flexural frame, shear wall or their combinations are used. using x form of cable bracing in order to strengthen concrete buildings is a new method. this system is more economical compared with the other systems due to cables low weight, high tensile resistance, easy performance and less maintenance problems. in this...

Dieses Papier befasst sich mit einer Studie über die Optimierungsmöglichkeiten von Anfragen auf verteilten Data Warehouse Architekturen mittels verschiedenartiger Verteilungsstrategien der beteiligten Tabellen am Beispiel SAP NetWeaver BI.