Mucocele, a common benign cystic lesion of minor salivary gland and associated ducts develops following extravasation or retention of mucous material in the subepithelial tissue. Occurrence of mucocele of tongue is considered less frequent when compared to a higher incidence of mucocele in the lower lip of young patients. Different modalities of treatment, such as conventional surgical excision...

Branching morphogenesis (BrM) is a basic developmental process for the formation of the lung, kidney, and all exocrine glands, including the salivary glands. This process proceeds as follows. An epithelial downgrowth invaginates into underlying mesenchyme, and forms a cleft at its distal end, which is the site of dichotomous branching and elongation; this process of clefting and elongation is r...

CASE A 44-year-old Indian woman presented with a painless left soft palate swelling of size 2×2 Cm for three years (Figure-1). The swelling was initially small and slowly increased its size. The overlying mucosa was slightly erythematous. The swelling was well circumscribed, smooth, firm in consistency and non-tender. Regional lymphadenopathy was present. A provisional diagnosis of salivary gla...

The present study was aimed to elucidate gross, histomorphological and histochemical status in parotid salivary gland of buffalo during neonatal life. The study was carried out on parotid salivary gland of eighteen buffalo neonates. These neonates were categorized into three groups based on their age, viz., Group-1: <1 month; Group-2: between1-2 months and Group-3: between 2-3 months. Macroscop...

Ranula is a benign mucous containing, thin walled swelling which is caused by either rupture or blockage of major or minor salivary gland ducts. We present a case of a healthy 46 year male patient who presented with a 14 days history of swelling under the tongue, accompanied by discomfort while swallowing. He revealed a history of trauma of the maxillofacial region 2 months earlier. Local exami...

Primary biliary cirrhosis (PBC) is a chronic progressive autoimmune cholestatic liver disease characterized by highly specific antimitochondrial antibodies (AMAs) and the specific immune-mediated injury of small intrahepatic bile ducts. Unique apoptotic feature of biliary epithelial cells (BECs) may contribute to apotope presentation to the immune system, causing unique tissue damage in PBC. Pe...

Minor salivary gland biopsy specimens from patients with Sjögren's syndrome (primary and secondary) and from normal controls were examined with the four step biotin-avidin-immunoperoxidase assay. The composition of the infiltrating cells was similar in patients with both primary and secondary Sjögren's syndrome, consisting primarily of T lymphocytes with predominance of T helper/inducer cells. ...

An 11-year-old female golden retriever dog had a mass at the right corner of the upper lip, which gradually increased in size and protruded into the oral cavity. The mass was removed surgically. The cut surface of the mass was smooth, whitish and solid, and covered by the oral mucosal membrane. Histopathologically, the mass consisted mainly of reticular pattern of short spindle cells that stain...