The Drosophila salivary gland is proving to be an excellent experimental system for understanding how cells commit to specific developmental programs and, once committed, how cells implement such decisions. Through genetic studies, the factors that determine where salivary glands will form, the number of cells committed to a salivary gland fate, and the distinction between the two major cell ty...

Objective: To assess the relationship between salivary pH and periodontitis in subjects with and without diabetes mellitus. The relationship between diabetes mellitus and salivary pH has been assessed. The relationship between periodontitis and salivary pH has been assessed.But the relationship between diabetes mellitus, periodontitis and salivary pH among adults has received less attention. Me...

Neurokinin A (NKA) evokes salivary secretion. Despite such reports, the direct effect of NKA on salivary secreteion in submandibular gland has not been clarified. Here we studied characterization of salivary fluid secretion induced by NKA in the perfused submandibular grand (SMG) of the rat. NKA (3-100 nM) stimulated salivary fluid secretion in a dose-dependent manner. The profile of secretion ...

although salivary alkaline phosphatase (alp) can balance de- and remineralization processes of enamel, there is no evidence regarding its effects on the concentrations of calcium and phosphate in saliva. the present study aims to determine the relationship between salivary alp activity and the concentrations of calcium and phosphate in saliva. in this cross-sectional study, we evaluated salivar...

background: the clinical symptoms of diabetes mellitus in oral cavity are xerostomia, pathological changes in periodontal tis­sues and caries. it has been suggested that the determination of salvia`s components in diabetic patients may be useful in de­scribing and further understanding the oral findings in this condition. the aim of this study was to detect differences be­tween the salivary alb...

sialolithiasis is a common disease of the major salivary glands, characterized by the obstruction of a salivary gland or its excretory duct due to the formation of calcareous concretions. sialoliths usually measure from 1 mm to <10 mm. they rarely measure more than 15 mm, and infrequently giant salivary gland calculi >15 mm have been reported in the literature. the submandibular gland and its d...

Sialolithasis is the most common salivary gland disease. A case of an unusually large sialolith arising in the submandibular gland is presented, along with a review of the management of giant salivary gland calculi.

The effects of ATP on salivary glands have been recognized since 1982. Functional and pharmacological studies of the P2 nucleotide receptors that mediate the effects of ATP and other extracellular nucleotides have been supported by the cloning of receptor cDNAs, by the expression of the receptor proteins, and by the identification in salivary gland cells of multiple P2 receptor subtypes. Curren...

Introduction. Decreased salivary flow and xerostomia are frequent findings in Parkinson's disease (PD), possibly caused by alterations in the parasympathetic tonus. Here we explore salivary acetylcholinesterase (AChE) activity as a potential biomarker in PD. Methods. We measured salivary flow, AChE activity, and total protein concentration in 30 PD patients and 49 healthy controls. We also perf...

Saliva of hematophagous leeches (Hirudo sp.) contains bioactive proteins which allow the leech proper feeding and storage of ingested blood, but may also exert effects in the host. Leech therapy is used to treat many different ailments in humans, although only a small fraction of salivary proteins are characterized yet. Moreover, we do not know whether complete transfer of salivary proteins sto...