1) External recording of cerebral clearance was performed after Kr85 saline solution injection into the common carotid artery. Clearance curve thus obtained was divided into 3 exponentials. The 3rd phase represents mainly clearance of the area perfused with external carotid artery and the rest of the curve after subtraction of the 3rd phase can be treated in the similar way to that of reported ...

BACKGROUND Cerebral edema is a potentially devastating complication of various acute neurologic disorders. Its successful treatment may save lives and preserve neurologic function. REVIEW SUMMARY Different pathophysiological mechanisms are responsible for the formation of cytotoxic and vasogenic edema. Yet, these 2 types of edema often coexist and their treatment tends to overlap, with the ex...

We have previously reported that there are inter-individual differences in the cardiovascular responses to experimental muscle pain, which are consistent over time: intramuscular infusion of hypertonic saline, causing pain lasting ~60 min, increases muscle sympathetic nerve activity (MSNA)-as well as blood pressure and heart rate-in certain subjects, but decrease it in others. Here, we tested t...

STUDY OBJECTIVE To analyze the cough response to three airway challenges in order to clarify whether the recording of the provoked coughs would be beneficial in the management of asthma. DESIGN A prospective study. SETTING University hospital. PARTICIPANTS Fifteen healthy subjects, 16 steroid-naïve subjects with asthma, and 16 subjects with steroid-treated asthma. INTERVENTIONS Inhalati...

Normal and malignant human cervical cancer cells were imaged in vivo with confocal, phase contrast, and brightfield microscopies. Results were compared between cells in growth medium before and after addition of acetic acid, hypertonic saline solution, toluidine blue, and Lugol's iodine. The exogenous agents changed the backscattering characteristics of the cells when measured with confocal mic...

SUMMARY Adult male Sprague-Dawley rats briefly immersed-n cold water and forced to swim showed Straub tail elevation, a typical s~gn of opiate stimu-iation, upon removal. The presence of Straub tail was a function of degree of immersion and was reversed by naloxone. Th~s suggests the Straub taft response may be a novel behavioral index of stress-indu~ed endorphin release. Stressful manipulation...

Intact mammalian neurofilaments were separated by centrifugation of osmotically shocked, desheathed segments of rat peripheral nerve. Neurofilament-rich supernates were incubated in different media with varying dilutions or dialysis of samples. Neurofilaments attached to carbon-Formvar-coated grids were exposed to similar incubations. The relative preservation or disruption of neurofilaments du...

Urinary sodium output increases in the first several days of fasting both in humans and rabbits. The major causal factor of the fasting-induced natriuresis was proposed to be glucagon (1), but the mechanism remains obscure. We have recently observed that fasting for one to four days resulted in the negative sodium balance in rats provided a low salt diet and saline (2). The fasting-induced natr...

background: acute kidney injury (aki) is a common and life-threatening complication following coronary artery bypass graft (cabg). neutrophil gelatinase-associated lipocalin (ngal) and cystatin c have shown to be good predictive factors for aki. recently, there has been a growing interest in the use of hypertonic saline in cardiac operations. the purpose of this study was to evaluate the prophy...

Sll?gested the clinical picture of cholera. . There had been no cases of cholera howevei 1,1 the village in which he lived. Without Raiting to make a diagnosis, 1 gave him two pints of hypertonic saline solution with glucose and adrenalin intravenously. I also ordered 10 minims of liquor adrenalin hydrochloride to be dropped under the tongue even l0ur for six doses. When I saw the patient six h...