Islamic Traditional Medicine (ITM) is a holistic system of medicine. Saffron (Crocus sativus) is one of the most famous plants cultivated in Iran and has a wide range of activities such as oxytocic, anti-carcinogenic, exhilarant, anti-depressant, and anti-asthma effects. In addition, saffron can increase the bioavailability and enhance absorption of other drugs. This study comprises a bibliogra...

Objective: In the present study, the effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference (CPP) in mice were investigated. Materials and Methods: Subcutaneous administration of morphine (40 mg/kg for four days) produced place preference. Intraperitoneal administration of aqueous extract (40 and 80 mg/kg for ...

BACKGROUND Crocus sativus L. (saffron) is used in folk medicine, for example as an antiedematogenic agent. We aimed to evaluate the antinociceptive and anti-inflammatory activity of saffron extracts in mice. RESULTS We used aqueous and ethanolic maceration extracts of Crocus sativus L. stigma and petals. Antinociceptive activity was examined using the hot plate and writhing tests. The effect ...

BACKGROUND Readiness of the cervix is required for successful induction of labor, and there are a number of ways in which this can be achieved. OBJECTIVES The aim of the present study was to assess whether taking saffron orally could have an effect on the cervical readiness (primary outcome) and some delivery and neonatal outcomes (secondary outcomes) in women in the stage of term pregnancy. ...

The objective of this study was to investigate the effects of saffron as a natural sunscreen and moisturizer. The pollens of the saffron were dried and powdered in a grinder. The experimental formulations included a homosalate (8%) lotion reference, lotions with 2, 4 and 8% of grinded saffron, and the control lotion base without saffron. The lotions containing saffron were prepared like homosal...

Modern medicine is currently marked by an increased interest in herbal pharmaceutical drugs traditionally applied folk a significant number of diseases. In this regard, saffron (Crocus sativus L. Iridaceae) particular importance. This paper presents the results study effects Azerbaijan-grown on blood level follicle-stimulating hormone (FSH) female rats, as well testosterone male rats. se...

Study the antioxidant properties of different parts saffron extract and their application in cream

Background: Saffron is widely used as a food flavor and has well known medicinal effects which have an effect on steroid and sexual hormones. The aim of present study was investigation of saffron orally administration on spermatogenesis index in stress induced rats. Materials and Methods: In present study, 160 male adult rats divided to four groups with 10 rats per each cage and with four repli...

OBJECTIVES The aim of the present study was to investigate immunotoxic effect of safranal (SAF), a main component of Crocus sativus essential oil, using Balb/c mice. MATERIALS AND METHODS SAF was administered intraperitoneally at doses of 0.1, 0.5 and 1 ml/kg for 3 weeks. Hystopathological examination of spleen and bone marrow, cellularity of spleen, delayed type of hypersensitivity (DTH) res...