Given a reconfigurable system X , such as a robot moving on a grid or a set of particles traversing a graph without colliding, the possible positions of X naturally form a cubical complex S(X). When S(X) is a CAT(0) space, we can explicitly construct the shortest path between any two points, for any of the four most natural metrics: distance, time, number of moves, and number of steps of simult...

The Federated Satellite Systems/ 3 Cat-5 (FSSCat) mission was the winner of European Space Agency (ESA) Sentinel Small (S ) Challenge and overall 2017 Copernicus Masters competition. It consisted two six-unit CubeSats. Earth observation payloads were 1) Flexible Microwave Payload 2 (FMPL-2) onbo...

Monoclonal antibody Cat-315 recognizes a chondroitin sulfate proteoglycan (CSPG) expressed on the surface of subsets of neurons in many areas of the mammalian CNS (). The cell type-specific expression exhibited by the Cat-315 CSPG and other perineuronal net CSPGs imparts a distinct molecular surface identity to a neuron (Celio and Blumcke, 1994; Lander et al., 1997). The cell type(s) producing ...

objective(s): the role of aluminum (al) in the pathogenesis of neurodegenerative diseases has been implicated in several studies. however, the exact mechanisms of cytotoxic effects of al have not been elucidated yet. the aim of this study was to investigate the effect of l-type calcium channel antagonist, nimodipine (nm), and lithium chloride (licl) on al-induced toxicity in pc12 cells. materia...

somerfield (this i s sue) calls for a basic shift in the focus of coping research. He points to the need for a more systemic conceptualization of stress and coping processes, the organization of studies of coping around homogeneous stressors, and the adoption of a pragmatic, microanalytic approach to both coping assessment and the analysis of the resulting data. His examples drawn from the stud...

Uma vez ocorrida a sensibilização, e a asma se manifestar clinicamente, a exposição persistente aos alérgenos se associa ao aparecimento de sintomas. Portanto, quando a doença já está estabelecida, a exposição ambiental aos alérgenos oferece risco de desencadear crises, dificultando a interpretação da associação entre a asma e a sensibilização alérgica como sendo de causa e efeito. Referências ...

Dihydrofolate reductase (DHFR) gene expression is required for cell growth. The DHFR gene promoter contains several GC elements capable of binding the transcription factor Sp1. In this report we have characterized the effect of protein(s) binding to these sequence elements in the Chinese hamster DHFR promoter on transcription. We have constructed a series of deletions containing from 896 to 103...

Let A 2 SL(2;Z) be the “Arnold’s cat map”(or any other hyperbolic element):