BACKGROUND Personal digital assistants (PDAs) allow healthcare professionals to check for potential drug-drug interactions (DDIs) at the point of care, reducing the need to consult traditional references. However, PDAs can only be as effective as the software programs they use. OBJECTIVE To examine the ability of DDI software programs manufactured for Palm OS-compatible PDAs in detecting clin...

Total body irradiation combined with chemotherapy is currently the most effective procedure as a preparative myeloablative regimen. However, resistance to radiotherapy and chemotherapy in refractory acute myeloid leukemia is associated with short-time recurrence after allogeneic hematopoietic stem cell transplantation. To address this issue, we used three cell lines, HL60, HL60/ADR (adriamycin-...

PURPOSE Microphthalmia, anophthalmia, and coloboma are ocular malformations with a significant genetic component. Rx is a homeobox gene expressed early in the developing retina and is important in retinal cell fate specification as well as stem cell proliferation. We screened a group of 24 patients with microphthalmia, coloboma, and/or anophthalmia for RX mutations. METHODS We used standard P...

Background. Ulcerative proctitis (UP) is typically treated initially with oral 5-aminosalicylate ("5-ASA"), mesalamine suppository, or mesalamine enema ("UP Rx"). Little is known about their effectiveness in practice. Methods. Using a US health insurance database, we identified new-onset UP patients between January 1, 2005, and December 31, 2007, based on the following: (1) initiation of UP Rx;...

RX J0720.4−3125 is the third brightest neutron star in the soft X-ray sky and has been a source of mystery since its discovery, as its long 8-s period separates it from the population of typical radio pulsars. Three models were proposed for this source: a neutron star accreting from the interstellar medium, an off-beam radio pulsar, or an old, cooling magnetar. Using data from Chandra, ROSAT, a...

In this section Okumura and Hata propagation models are discussed. The two models or their modified version are frequently used throughout commercially available RF engineering tools. 1.1 Okumura Propagation Model Okumura's model is one of the most frequently used macroscopic propagation models. It was developed during the mid 1960's as the result of large-scale studies conducted in and around ...

Direct-sequence code division multiple access (DS-CDMA) is a promising uplink access technology for broadband cellular mobile communication systems. In this paper, we propose a joint transmit (Tx)/iterative receive (Rx) frequency-domain equalization (FDE) for DS-CDMA. In the proposed scheme, simple one-tap FDE at the transmitter and iterative one-tap FDE at the receiver are jointly performed us...

OBJECTIVE To assess experimental virulence among sequence type 131 (ST131) Escherichia coli bloodstream isolates in relation to virulence genotype and subclone. METHODS We analysed 48 Spanish ST131 bloodstream isolates (2010) by PCR for ST131 subclone status (H30Rx, H30 non-Rx, or non-H30), virulence genes (VGs), and O-type. Then we compared these traits with virulence in a murine sepsis mode...

RX J1856.5−3754, a bright soft X-ray source believed to be the nearest thermally emitting neutron star, has commanded and continues to command intense interest from X-ray missions. One of the main goals is to determine the radius of this neutron star. An integral part of the determination is an accurate parallax. Walter (2001) analyzed Hubble Space Telescope (HST ) data and derived a parallax, ...

The Hemochron Rx/Dx uses an ACT and a heparin response tube to calculate the heparin dose to identify heparin sensitive/resistant patients. We evaluated the Rx/Dx system in 37 patients to determine if the ACT after the predicted heparin loading dose was adequate to initiate CPB. The mean heparin dose calculated by the Rx/Dx was 31,700 IU ± 8,700 IU (370 IU/kg) with a mean post ACT of 463 ± 124 ...