BACKGROUND Rosacea is a common chronic skin condition that manifests as recurrent inflammatory lesions. Long-term treatment is required to control symptoms and disease progression, with topical treatments being the first-line choice. Ivermectin 1 % cream is a new once-daily (QD) topical treatment for the inflammatory lesions of rosacea, and it is important to compare the efficacy, safety, and t...

OBJECTIVE To compare the efficacy of intense pulsed light (IPL) (540-950 nm) in treating different erythema associated with rosacea. METHODS Thirty-two patients with erythematotelangiectatic rosacea (ETR) (n = 16) and papulopustular rosacea (PPR, n = 16) were recruited. Three treatments of IPL (540-950 nm) were administered on the face at 3-week intervals. Clinical improvement in erythema was...

1. Barco D, Alomar A. Rosácea. Actas Dermosiilogr. 2008;99:244-56. 2. Chen AY, Zirwas MJ. Steroid-induced rosacealike dermatitis: case report and review of the literature. Cutis. 2009;83:198204. 3. Ioannides D, Lazaridou E, Apalla Z, Devliotou-Panagiotidou D. Phosphodiesterase-5 inhibitors and rosacea: report of 10 cases. Br J Dermatol. 2009;160:719-20. 4. Hagman JH, Ginebra A, Pieminte P, Fras...

Ataxia-Telangiectasia is a rare multisystem autosomal recessive disorder [OMIM 208900], caused by mutations in Ataxia-Telangiectasia Mutated gene. It is characterized by neurological, immunological and cutaneous involvement. Granulomas have been previously reported in Ataxia-Telangiectasia patients, even if acne rosacea has not been described.We report a case of a young Ataxia-Telangiectasia pa...

OBJECTIVE To increase awareness of the oculocutaneous manifestations of two common skin diseases. QUALITY OF EVIDENCE We reviewed clinically relevant articles from the dermatologic and ophthalmologic literature. The PubMed database was searched from January 1965 to January 2001 to locate retrospective and prospective cohort and descriptive studies using the MeSH terms acne rosacea; eczema; an...

Tetra-carboxy-methyl-naringenin-chalcone (TCM-NC) is a new cosmetic active derived from naringenin, a flavanone naturally occurring in the peel of citrus fruit and tomato skin. The naringenin isomer naringenin-chalcone has been reported to have potent anti-allergic properties. For this reason the effect of TCM-NC was studied in an in vitro assay mimicking the inflammation pathway of rosacea ski...

Rosacea is a chronic inflammatory skin condition that predominantly affects the skin of the face and the eyes. Several factors are associated with the onset and persistence of the condition, including an altered immune response in the skin and elevated levels of Demodex mites. Alterations in the immune response include elevated levels of LL-37 in rosacea skin, increased expression of TLR-2 and ...

BACKGROUND Rosacea treatments including oral/topical medications and laser therapy are numerous but unsatisfactory. OBJECTIVE To compare the effectiveness of the dual wavelength long-pulsed 755-nm alexandrite/1,064-nm neodymium: yttrium-aluminum-garnet laser (LPAN) with that of 585-nm pulsed dye laser (PDL) for rosacea. METHODS This was a randomized, single-blinded, comparative study. Full ...

OBJECTIVE To examine the possible associations between Demodex folliculorum and a number of skin diseases. METHODS Standardized skin surface biopsy samples were obtained from the cheeks of 144 patients with histopathologically proven basal cell carcinoma (BCC, n = 27), squamous cell carcinoma (SCC, n = 28), melanoma (n = 23), discoid lupus erythematosus (DLE, n = 32), and rosacea (n = 34). Th...