نتایج جستجو برای: rock mechanics
تعداد نتایج: 179240 فیلتر نتایج به سال:
Osteogenic differentiation of human mesenchymal stem cells (hMSCs) is classically thought to be mediated by different cytokines such as the bone morphogenetic proteins (BMPs). Here, we report that cell adhesion to extracellular matrix (ECM), and its effects on cell shape and cytoskeletal mechanics, regulates BMP-induced signaling and osteogenic differentiation of hMSCs. Using micropatterned sub...
While is widely acknowledged that nonmuscle myosin II (NMMII) enables stress fibers (SFs) to generate traction forces against the extracellular matrix, little is known about how specific NMMII isoforms and functional domains contribute to SF mechanics. Here we combine biophotonic and genetic approaches to address these open questions. First, we suppress the NMMII isoforms MIIA and MIIB and appl...
[1] Acoustic emissions and tremor‐like signals are widely recorded in laboratory experiments. We are able to isolate the physical origins of these signals using high resolution nanoseismic analysis. The use of a picometer‐sensitive, wide‐band sensor array permits us to determine force‐time functions and focal mechanisms for discrete events found amid the “noise” of friction, similar to how low ...
چکیده ندارد.
Abstract Rock-socket pile design predominantly depends on the shaft resistance to support load at serviceability state. However, due limited understanding of pile–rock interactions, capacity is normally calculated using empirical correlations. In this study, load-bearing mechanisms rock-socketed piles were investigated through a miniaturised pile–load test setup in soft synthetic rock. X-ray CT...
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