Dietary intervention to prevent colon cancer is a major health issue. At present it is not clear which dietary factors modify colon cancer risk. Caloric restriction reduces the incidence of many spontaneous and car cinogen-induced tumors in rodents, but its role in human carcinogenesis is unknown. The relationships of body mass index (BMI), body composition, and resting metabolic rate (RMR) to ...

BACKGROUND Circadian rhythm has been shown to be related to glucose metabolism and risk of diabetes, probably through effects on energy balance. Recent genome-wide association studies identified variants in circadian rhythm-related genes (CRY2 and MTNR1B) associated with glucose homeostasis. OBJECTIVE We tested whether CRY2 and MTNR1B genotypes affected changes in measures of energy expenditu...

Glucose metabolism has been shown to be increased in neoplastic tissue. It has been suggested that high activity of glucose metabolism is associated with a high grade of malignancy of human cancer. We studied in vivo glucose metabolism in 22 patients with untreated non-Hodgkin's lymphoma with fluorine-18-fluorodeoxyglucose (FDG) and positron emission tomography (PET). FDG uptake in lymphoma dep...

BACKGROUND There are strong logical reasons why energy expended in metabolism should influence the energy acquired in food-intake behavior. However, the relation has never been established, and it is not known why certain people experience hunger in the presence of large amounts of body energy. OBJECTIVE We investigated the effect of the resting metabolic rate (RMR) on objective measures of w...

BACKGROUND There is increasing evidence to suggest that a vegetarian diet low in fat and high in complex carbohydrates offers the potential for decreasing the risk of chronic disease. However, there is little information about the effect of vegetarian diets on resting metabolic rate (RMR). The objective of this study was to determine the association of vegan diet with RMR and body composition a...

In geographically widespread ectotherms, variation in life history phenotypes may be caused by differences in maintenance metabolism of individuals. I estimated daily and annual maintenance metabolism of eastern fence lizards, Sceloporus undulatus, from two populations with markedly different life histories; lizards in South Carolina grow faster, mature earlier, and have greater annual reproduc...

Given the ubiquity and evolutionary importance of parasites, their effect on the energy budget of mammals remains surprisingly unclear. The eastern chipmunk (Tamias striatus (L., 1758)) is a burrowing rodent that is commonly infected by cuterebrid bot fly (Cuterebra emasculator Fitch, 1856) larvae. We measured resting metabolic rate (RMR) and cold-induced VO2-max (under heliox atmosphere) in 20...

PURPOSE To compare intensity misclassification and activity MET values using measured RMR (measMET) compared with 3.5 ml x kg(-1) x min(-1) (standMET) and corrected METs [corrMET = mean standMET x (3.5 / Harris-Benedict RMR)] in subgroups. METHODS RMR was measured for 252 subjects following a 4-hr fast and before completion of 11 activities. VO2 was measured during activity using indirect cal...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 239 1. Diet Intervention Studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241 1.1 Dietary Energy Restriction and Resting Metabolic Rate (RMR...

Recent empirical and conceptual papers have highlighted the potential for metabolism to act as a proximate mechanism for behavior that could explain animal personality (consistency over time). Under this hypothesis, individuals with consistently high levels of behavioral activity should also have high resting metabolic rate (RMR) as it can reflect capacity to process food and generate energy. W...