abstract background: pregnancy is associated with many physiological changes, which in some cases may cause serious risks such as preeclampsia, and fetal and maternal health threats. recent research has focused on the relationship between metabolic syndrome and preeclampsia. by identifying appropriate indicators for early diagnosis, maternal–fetal complications can be prevented. the present stu...

Background: Predicting adverse neurovascular complications due to diabetic ketoacidosis (DKA) particularly in children leads to more appropriately management of disease as well as achievement of acceptable patients' survival. Cerebral edema is a life-threatening adverse event following DKA responsible for high mortality rate. Recently, authors have focused introducing new risk assessment tools ...

A simple normative theory is proposed for the responsible management of risks to the public. A ‘lifesaving’ alternative, if it is truly to save lives, should return to the community more years of life expectancy in good health than the years of work consumed to pay for its cost. This common-sense time principle of risk management provides a criterion for acceptable risk that is applicable in co...

Assessment of the health impacts of recreational water quality is a useful tool in developing appropriate policies. Risk assessment approaches are increasingly being used as a scientific rationale for risk management. This chapter describes the various methods used for identification and quantification of hazards in recreational water risk assessment. It also looks at how different factors infl...

We investigate optimal system design in a multi-location system in which supply is subject to disruptions. We examine the expected costs and cost variances of the system in both a centralized and a decentralized inventory system. We show that, when demand is deterministic and supply may be disrupted, using a decentralized inventory design reduces cost variance through the risk diversification e...

The paper provides novel insights on the effect of a firm’s risk management objective on the optimal design of risk transfer instruments. I analyze the interrelation between the structure of the optimal insurance contract and the firm’s objective to minimize the required equity it has to hold to accommodate losses in the presence of multiple risks and moral hazard. In contrast to the case of ri...

World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being rela...