We investigated supports for the final doublets of ATF2 with vertical relative motion to the floor of final doublets below 10nm. Our calculations of relative motion were done by using data of ATF ground motion. We studied the vibratory behaviour of a steel lightweight honeycomb table as a base for fixing magnets. First, the table was fixed to the floor by four steel feet at its corners. Its fir...

A rigid map u : Ω ⊂ R → R is a Lipschitz-continuous map with the property that at every x ∈ Ω where u is differentiable then its gradient Du(x) is an orthogonal m × n matrix. If Ω is convex, then u is globally a short map, in the sense that |u(x) − u(y)| ≤ |x − y| for every x, y ∈ Ω; while locally, around any point of continuity of the gradient, u is an isometry. Our motivation to introduce Lip...

A major complication of factor replacement therapy for haemophilia is the development of anti-factor neutralizing antibodies (inhibitors). Here we show that liver gene therapy by lentiviral vectors (LVs) expressing factor IX (FIX) strongly reduces pre-existing anti-FIX antibodies and eradicates FIX inhibitors in haemophilia B mice. Concomitantly, plasma FIX levels and clotting activity rose to ...

Emerging successful clinical data on gene therapy using adeno-associated viral (AAV) vector for hemophilia B (HB) showed that the risk of cellular immune response to vector capsid is clearly dose dependent. To decrease the vector dose, we explored AAV-8 (1-3 × 10(12) vg/kg) encoding a hyperfunctional factor IX (FIX-Padua, arginine 338 to leucine) in FIX inhibitor-prone HB dogs. Two naïve HB dog...

We show that the FIX type theory introduced by Crole and Pitts 3] can be encoded in variants of Abadi and Cardelli's object calculi. More precisely, we show that the FIX type theory presented with judgements of both equality and operational reduction can be translated into object calculi, and the translation proved sound. In the case of operational reductions, we introduce a variant of Abadi an...

Then Strang and Fix conditions are recalled and proved. The Strang and Fix conditions caracterize the approximating properties of a shift invariant localized operator by its ability to reconstruct polynomials. In particular, it is used to relate the number of vanishing moments of a wavelet to the order of approximation provided by the corresponding multiresolution analysis. Article [1] is gener...

this paper describe the three dimensional finite element modeling and buckling analysis ofconventional pallet racking system with semi rigid connection. in this study threedimensional models of conventional pallet racking system were prepared using the finiteelement program ansys and finite element analysis carried out on conventional pallet rackswith the 18 types of column sections developed a...

In this paper we show how translation from QVT-R to an intermediate semantic representation can be used to support analysis of QVT-R specifications. We use the UML to RDB case study to illustrate the approach.