Interindividual variability in drug responses and disease susceptibility is common in the clinic. Currently, personalized medicine is highly valued, the idea being to prescribe the right medicine to the right patient. Metabolomics has been increasingly applied in evaluating the therapeutic outcomes of clinical drugs by correlating the baseline metabolic profiles of patients with their responses...

Precision medicine aims to identify the right drug, for the right patient, at the right dose, at the right time, which is particularly important in cancer therapy. Problems such as the variability of treatment response and resistance to medication have been long-standing challenges in oncology, especially for development of new medications. Solid tumors, unlike hematologic malignancies or brain...

The value of health care can be increased tremendously through individualized medicine. With the promise of individualized medicine, healthcare professionals will be able to better predict disease risk, prevent development of disease and manage treatments more efficiently thereby allowing people to be healthier and active longer. The developments in the area of pharmacogenetics/pharmacogenomics...

INTRODUCTION Mesenteric phlebosclerosis is a rare ischemic disease affecting the colon. Systemic disease and herbal medicine have been pointed out as possible causes, and the disease is characterized by calcifications involved the mesocolic veins. Patients who do not respond to conservative therapy require surgical treatment. In surgical intervention, an adequate extent of colonic resection is ...

nuclear medicine imaging is routinely used for evaluation of perfusion and function of the transplanted kidneys. at present, the radiopharmaceutical of choice for this study in our center is tc 99m-ec. complications of the kidney graft are demonstrable in the early and delayed images. one of these complications is vesicoureteral reflux to the graft or to the native kidneys. we present a 27 year...

conclusions: according to our experiment, onion has an inhibitory effect on the growth of normal eye flora; although the duration of onion juice instillation did not show any significant effect on the group results. hence, this finding is an initiating point for further investigations into the antimicrobial properties of this herb to treat common eye infections, including conjunctivitis and ble...

It has been recently argued that knowledge is the norm of practical reasoning. A way of formulating this norm is the following bi-conditional: it is rational to treat p as a reason for acting if and only if you know that p. In my talk, I provide three new counterexamples to this claim. I show cases of rational action: i) motivated by imagining, ii) grounded in acceptance, and iii) performed in ...