RATIONALE Sulfur mustard (SM) is a frequently used chemical warfare agent, even in modern history. SM inhalation causes significant respiratory tract injury, with early complications due to airway obstructive bronchial casts, akin to those seen after smoke inhalation and in single-ventricle physiology. This process with SM is poorly understood because animal models are unavailable. OBJECTIVES...

Background: One of the most significant factors in the success of dental implant procedures, can be mentioned by the quality and quantity of jaw bone. The occurrence of some problems such as trauma, infection, pathological lesions and the long-term absence of teeth in patients, it causes irregularities in the jaw bone and can get bone resorption. Sever defects after trauma or tumor resection ne...

BACKGROUND Activated factor XIII (FXIIIa), a transglutaminase, introduces fibrin-fibrin and fibrin-inhibitor cross-links, resulting in more mechanically stable clots. The impact of cross-linking on resistance to fibrinolysis has proved challenging to evaluate quantitatively. METHODS We used a whole blood model thrombus system to characterize the role of cross-linking in resistance to fibrinol...

Platelet-rich plasma (PRP) has been used as a therapeutic tool to promote wound healing, in orthopedics, dermatology, oral surgery, etc. However, the mechanisms underlying the wound healing effects of PRP remain unclear. The purpose of this study was to evaluate the effectiveness of applying PRP, particularly in the management of tooth extraction sockets. Thr...

Purpose: To do a clinical evaluation of the results of the treatment of multiple adjacent gingival recessions with VISTA technique (Vestibular Incision Subperiostal Tunnel Access) and platelet-rich fibrin membrane (PRF m). Methods and materials: The study included 30 participants (19 women and 11 men) with multiple adjacent gingival recessions on both jaws of Miller’s Class I and Class II. The ...

Platelet-rich fibrin (PRF) clots have been used in regenerative dentistry most often, with the assumption that growth factor levels are concentrated in proportion to the platelet concentration. Platelet counts in PRF are generally determined indirectly by platelet counting in other liquid fractions. This study shows a method for direct estimation of platelet counts in PRF. To validate this meth...

BACKGROUND AND PURPOSE Although thromboembolic stroke is caused by red, white, or mixed clots, the emboli previously used in animal studies on thrombolysis were more often red than white. Because this might be one of the reasons why thrombolysis is less effective in patients than in experimental stroke, we developed a new method of preparing highly standardized red and fibrin-rich white emboli....