One of the more surprising recent discoveries in glial biology has been that oligodendrocytes (OLs) originate from very restricted regions of the embryonic neural tube. This was surprising because myelinating OLs are widespread in the mature central nervous system, so there was no reason to suspect that their precursors should be restricted. What we now know about early OL development suggests ...

Nature frequently utilizes opposing factors to create a stable activator gradient to robustly control pattern formation. This study employs a biomimicry approach, by delivery of both angiogenic and antiangiogenic factors from spatially restricted zones of a synthetic polymer to achieve temporally stable and spatially restricted angiogenic zones in vivo. The simultaneous release of the two spati...

background: coronary heart disease is one of the most important problems of public health. one risk factor is dyslipidemia. evidence from molecular and animal research and epidemiologic investigations indicate that calcium intake may influence lipid metabolism.but intervention studies have produced conflicting results.objective of this study was to determine the effects of calcium supplementati...

for a polynomial p(z) of degree n, having all zeros in |z|< k, k< 1, dewan et al [k. k. dewan, n. singh and a. mir, extension of some polynomial inequalities to the polar derivative, j. math. anal. appl. 352 (2009) 807-815] obtained inequality between the polar derivative of p(z) and maximum modulus of p(z). in this paper we improve and extend the above inequality. our result generalizes certai...

in this study, a total of 101,147 monthly test day records of somatic cell count collected from 13,977 first lactation holstein cows (in 183 herds) calved between 2002 and 2006 were used. for the genetic analysis, a random regression test day model was utilized. somatic cell score (scs) was calculated based on natural logarithm of somatic cell count. in the model, fixed effect of contemporary g...

this research used the test day data of the milk production of holstein cows from golestan, mazandaran and guilan provinces collected by animal breeding center of iran between the years of 1988-2011. permanent effects of model, including cattle blend, breeding year and season, also percent of holstein gene and age during recording, were used as a secondary variable. all data obtained in this re...

The cerebellum participates in motor coordination as well as in numerous cerebral processes, including temporal discrimination. Animals can predict daily timing of food availability, as manifested by food-anticipatory activity under restricted feeding. By studying ex vivo clock gene expression by in situ hybridization and recording in vitro Per1-luciferase bioluminescence, we report that the ce...

We have studied the molecular karyotypes of 21 strains and 14 clones of Leishmania infantum using pulsed field gel electrophoresis (PFGE). We detected a high degree of polymorphism within this species, with 'strain-specific' patterns for most isolates, even within a restricted endemic area. Variations relate to both the size of chromosomes (270-2600 kb) and their number, which can vary from 24 ...

The appearance of variations in the protein profile of Ostertagia ostertagi (Stiles, 1892) infective larvae (L3), which were induced by hypobiosis triggering factors, was evaluated by means of SDS-PAGE and densitometric analysis. Area integration analyses of their protein profiles was carried out between 66 and 77 kDa. Important quantitative variations were identified in the protein levels of t...