Accurate localization and uptake quantification of lesions in the chest and abdomen using PET imaging is challenged by respiratory motion occurring during the exam. This work describes how a stack-of-stars MRI acquisition on integrated PET/MRI systems can be used to derive a high-resolution motion model, how many respiratory phases need to be differentiated, how much MRI scan time is required, ...

UNLABELLED Several studies have described nonuniform blurring of myocardial perfusion imaging (MPI) due to respiration. This article describes a technique for correcting the respiration effect and assesses its effectiveness in clinical studies. METHODS Simulated phantoms, physical phantoms, and patient scans were used in this study. A heart phantom, which oscillated back and forth, was used t...

INTRODUCTION: Patient motion, especially respiratory and cardiac motion, leads to artifacts which could damage the quality of Magnetic Resonance Imaging (MRI) and make the resulting diagnosis less accurate. If such motion occurs during MRI acquisitions, it has been shown that, knowing this motion, it is possible to invert the process of artifact production and to reconstruct a motion compensate...

State of the art radiation treatment methods such as hypo-fractionated stereotactic body radiation therapy (SBRT) can successfully destroy tumor cells and avoid damaging healthy tissue by delivering high-level radiation dose that precisely conforms to the tumor shape. Though these methods work well for stationary tumors, SBRT dose delivery is particularly susceptible to organ motion, and few te...

Microcomputed tomography (Micro-CT) has the potential to noninvasively image the structure of organs in rodent models with high spatial resolution and relatively short image acquisition times. However, motion artifacts associated with the normal respiratory motion of the animal may arise when imaging the abdomen or thorax. To reduce these artifacts and the accompanying loss of spatial resolutio...

Long acquisition times of several seconds lead to image artifacts in cardiac C-arm CT. While ECG gating is able to select a certain heart phase, residual artifacts are mostly caused by respiratory motion. In order to improve image quality, it is important to accurately estimate the breathing motion that occurred during image acquisition. It has been shown that diaphragmmotion is correlated to t...

In PET/CT thoracic imaging, respiratory motion reduces image quality. A solution consists in performing respiratory gated PET acquisitions. The aim of this study was to generate clinically realistic Monte-Carlo respiratory PET data, obtained using the 4D-NCAT numerical phantom and the GATE simulation tool, to assess the impact of respiratory motion and respiratory-motion compensation in PET on ...

In C-arm CT 3-D liver imaging, breathing leads to motion artifacts due to the relatively long acquisition time. Often, even with breath-holding residual respiratory motion can be observed. These artifacts manifest in blurring and interfere clinical investigations such as liver tissue imaging. For 3-D medical image reconstruction a respiratory motion estimation and compensation is required. In t...

BACKGROUND MRI physics simulators have been developed in the past for optimizing imaging protocols and for training purposes. However, these simulators have only addressed motion within a limited scope. The purpose of this study was the incorporation of realistic motion, such as cardiac motion, respiratory motion and flow, within MRI simulations in a high performance multi-GPU environment. ME...