cyclophosphamide (cp) is one of the anti-neoplastic drugs. despite its numerous clinical applications, it has devastating effects on the testicles and declines the sperm quality in treated patients. this study was aimed to investigate the protective effect of crocin in improving the toxicity induced by cp in reproductive system. in this study, 24 male adult mice (6 to 8 weeks) were randomly div...

objective: evaluation of the effects of different doses of antioxidant taurine on oxidative stress and human sperm parameters following cryopreservation. materials and methods: the semen of 20 fertile men were divided to 5 aliquot, one part considered as a fresh after analysis of standard semen parameters (motility, abnormal morphology, viability) and protamine deficiency, dna damage and measu...

the purpose of this study was to evaluate the probable effects of the vitamin e addition in different levels to the extender of chicken semen on spermatozoa quality during storage of semen at 4°c for 0, 3, 6, 10 and 24 hours. eight young ross broiler breeder strain 308 roosters were used in this experiment. the collected semen from all roosters was mixed together and diluted with modified a rin...

s:2011:"Background: Imidacloprid (IMD) is a systemic insecticide which acts as an insect neurotoxin and belongs to a class of chemicals called the neonicotinoids which act on the central nervous system of insects. According to previous studies, IMD is rated as "moderately toxic" on an acute oral basis to mammals and according to United States Environmental Protection Agency this compound is cla...

introduction: cryopreservation of single human spermatozoa is a new technique designed to improve the management of male infertility, it was first introduced in 1997 and was reported by others latter. the aim of this research was to evaluate the efficiency of this method in preserving either ejaculated or surgically retrieved spermatozoae. materials and methods: spermatozoae were obtained from ...

Background: Low levels of reactive oxygen species (ROS) and calcium are necessary for sperm function. NADPH oxidase 5 (NOX5) is a membrane enzyme which produces ROS. This enzyme is dependent on calcium for its activity. We investigated the importance of NOX5 and an important calcium channel (CatSper) on sperm function.Methods: This laboratory in-vitro study was done in Shiraz, Iran, 2016. Norma...

background: diabetes mellitus (dm), primary or idiopathic is a chronic disorder of the carbohydrate, lipid and protein metabolism. dm may impact male reproductive function at several levels. it is shown that dm has detrimental effects on sperm parameters in human and experimental animals. objective: the aim of this study was to observe the effects of diabetes on sperm parameters (viability, cou...

Background: Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on health, leading to reduced life expectancy and/or increased health problems such as infertility and sub fertility. Lipid peroxidation contributes to the damage of the sperm plasma membrane and result to infertility. In this study effects of Antioxidants (E, C, ...

background: bleomycin (bl) is a glycopeptide antibiotic obtained from the bacterium streptomyces verticillus which is routinely used for treatment of human cancers. royal jelly (rj) is a production from the hypo pharyngeal, mandibular and post cerebral glands of nurse bees. rj consists of 66% water, 15% sugars, 5% lipids, and 13% proteins, essential amino acids and vitamins. objective: the aim ...

In the hen oviduct, tubules have been identified that preserve the sperm, maintaining viability for up to 15 weeks. This study aimed to evaluate the physiological status of rooster sperm when preserved in vitro with uterus vaginal junction secretions (UVJS). Males and females of the Rhode Island breed were used. Sperm aliquots were prepared using Lake extender and Lake extender with UV...