BACKGROUND The goal of limb-sparing surgery for a soft tissue sarcoma of the extremity is to remove all malignant cells while preserving limb function. After initial surgery, microscopic residual disease in the tumor bed will cause a local recurrence in approximately 33% of patients with sarcoma. To help identify these patients, the authors developed an in vivo imaging system to investigate the...

Background: In patients with a congenital or developmental limb-length discrepancy, the short limb grows at a rate proportional to that of the normal, long limb. This is the basis of predicting limb-length discrepancy with existing methods, which are complicated and require multiple data points. The purpose of our study was to derive a simple arithmetic formula that can easily and accurately pr...

Limb-Length Discrepancy and Lower Limb Alignment The minimum threshold for treating limb-length discrepancy is debatable. In the study by O’Brien et al., an imposed discrepancy of >10 mm was perceived by twenty-nine (97%) of thirty normal subjects1. In the study by Golightly et al., an inequality of ‡20 mm was associated with progressive radiographic osteoarthritis of the knee2. There are subtl...

TO THE EDITOR: In their recent paper, Cornachione et al. (1) draw three major conclusions: 1) that cardiac myofibrils do not show static tension or residual force enhancement; 2) that static tension/residual force enhancement is directly related to titin isoforms; and 3) that static tension/residual force enhancement is not associated with titin-actin interactions. Here, I would like to point o...

Advances in robotic technology have recently enabled the development of powered lower-limb prosthetic limbs. A major hurdle in developing commercially successful powered prostheses is the control interface. Myoelectric signals are one way for prosthetic users to provide feedforward volitional control of prosthesis mechanics. The goal of this study was to assess motor learning in people with low...

developing supernumerary limbs is a rare congenital condition that only a few cases have been documented. depending on the cause and developmental conditions, they may be single, multiple or complicated, and occur as a syndrome or associated with other anomalies. polymelia is defined as the presence of extra limb(s) which have been reported in human, mouse, chicken, calf and lamb. it seems that...

BACKGROUND Malunion and nonunion of an ankle fusion site are associated with pain, osteomyelitis, limblength discrepancy, and deformity. The Ilizarov reconstruction has been used to treat these challenging problems. METHODS We reviewed the results in twenty-one ankles that had undergone a revision of a failed fusion, with simultaneous treatment of coexisting pathologic conditions, with use of...