نتایج جستجو برای: requisite variety
تعداد نتایج: 276094 فیلتر نتایج به سال:
Electronic markets have a short but dynamic history. How an electronic market can be successfully developed remains in dispute. There is a clear need to better understand the nature of electronic markets themselves and, in particular, to review important developments in their conceptualisation. To enable a deeper understanding of these issues, we decided to restrict our investigation to electro...
A dvances in medicine are driven by propagation of research and dissemination of meaningful results from basic science, clinical, or translational studies. Although a randomized controlled trial has the highest power, this is not the most frequently conducted study method in surgery, as randomized trials are often not feasible due to disease infrequen-cy or an inability to conduct an ethically ...
RATIONALE In the working heart, coronary blood flow is linked to the production of metabolites, which modulate tone of smooth muscle in a redox-dependent manner. Voltage-gated potassium channels (Kv), which play a role in controlling membrane potential in vascular smooth muscle, have certain members that are redox-sensitive. OBJECTIVE To determine the role of redox-sensitive Kv1.5 channels in...
Background—a-Adrenergic activation in vivo causes constriction of coronary arterioles, but, paradoxically, in vitro these microvessels do not contract to this stimulus. We hypothesized that cardiac myocytes have a requisite role in a1-adrenergic coronary arteriolar constriction through the release of myocyte-derived contractile factor(s). Methods and Results—Administration of the a1-adrenergic ...
Tibial stems are necessary in most total knee revisions to share the load and protect the fixation interface of the tibial tray. Successful use of a tibial stem requires independent stability of the stem with or without cement. Some additional geometry on the undersurface of the tibial tray such as peripheral pegs or fins is necessary to provide additional resistance to rotatory stresses if the...
BACKGROUND Alpha-adrenergic activation in vivo causes constriction of coronary arterioles, but, paradoxically, in vitro these microvessels do not contract to this stimulus. We hypothesized that cardiac myocytes have a requisite role in alpha1-adrenergic coronary arteriolar constriction through the release of myocyte-derived contractile factor(s). METHODS AND RESULTS Administration of the alph...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید