A 37-year-old Brazilian black male with a history of sickle cell anemia presented with a 2-week history of pain and edema in the lower extremities, accompanied by generalized weakness and dyspnea on exertion. Outpatient laboratory evaluation revealed hemoglobin of 4.3 mg/dl, creatinine of 5.8 mg/dl, and blood urea nitrogen of 100 mg/dl. Ten months prior to admission, he had been hospitalized fo...

Renal endothelin-1 participates in sodium and water handling, and its urinary excretion is increased in sodium-retentive states. We compared the cortical and medullary renal expression of prepro-endothelin-1, endothelin-converting enzyme-1, and endothelin type A and type B receptors in patients who underwent nephrectomy after normal (108 mmol/d NaCl; n=6) or low (20 mmol/d NaCl; n=6) sodium die...

OBJECTIVE To study the diagnostic yield of specimen obtained by percutaneous renal biopsy (PRB) under CT guidance and Ultrasound (US) guidance. METHODS This study was conducted at the department of Nephrology at Liaquat National Hospital and Dr. Ziauddin Hospital, Karachi. Renal biopsy specimens obtained between January 2007 and September 2009 were studied for number of glomeruli obtained. In...

Objective- To consider the possibility of ultrasonography evaluation of the plantar tendonsand ligaments and prepare a standard reference for it.Design- Descriptive studyAnimals- 7 female healthy Caspian miniature horses'-age 7year- no clinical sign of lamenessand prior to presentation.Procedure- The ultrasonography of the right and the left metatarsal region was performedusing a Pie Medical 10...

Potential benefits of statins in the treatment of chronic kidney disease beyond lipid-lowering effects have been described. However, molecular mechanisms involved in renoprotective actions of statins have not been fully elucidated. We questioned whether statins influence development of diabetic nephropathy through reactive oxygen species, RhoA and Akt/GSK3 pathway, known to be important in rena...

DIMITROV, R., P. YONKOVA and K. STAMATOVA, 2010. Comparative ultrasonogarphic study on prostate and bulbourethral glands of tomcat. Bulg. J. Agric. Sci., 16: 521-525 12 sexually matured, clinically healthy European short hair tomcats, aged from one to two years, were studied. Transabdominal prepubic sonographic approach was used. The prostate gland was observed in three views. A perineal sonogr...

A method for preparing highly purified glutaminase (EC 3.5.1.2, L-glutamine amidohydrolase) from pig renal cortex is described. The main steps consist of sodium sulfate fractionation followed by alternative solubilization by dialysis against Tris-HCI buffer and precipitation with phosphateborate. The linal enzyme preparation contains no impurities which could be detected by sucrose gradient cen...

Introduction:Darifenacin is a medication that has anticholinergic and antimuscarinic effects used in the treatment of overactive bladder.Adverse overdose such as dry mouth eyes,headache,nausea, constipation, urinary retention, dyspepsia have been reported .An effect on AKI not literature, no dose adjustment recommended patients with renal impairment
 Case:A 24-year-old male patient applied...