نتایج جستجو برای: rem gene

تعداد نتایج: 1163193  

Journal: :Journal of child and adolescent psychopharmacology 2011
Ashura Williams Buckley Kenneth Sassower Alcibiades J Rodriguez Kaitlin Jennison Katherine Wingert Jack Buckley Audrey Thurm Susumu Sato Susan Swedo

BACKGROUND Rapid eye movement (REM) sleep is greatest in the developing brain, is driven by acetylcholine, and may represent a protected time for neuroplasticity. Recently published data from our lab observed that children with autism spent significantly less time in this state during a single night recording than did typically developing children and those with developmental delay without auti...

Journal: :Journal of neurophysiology 2004
Jagadish Ulloor Vijayakumar Mavanji Subhash Saha Donald F Siwek Subimal Datta

Considerable evidence suggests that the neurotransmitter gamma-aminobutyric acid (GABA)-ergic system and pedunculopontine tegmentum (PPT) in the brain stem are critically involved in the regulation of rapid-eye-movement (REM) sleep. GABA and its various receptors are normally present in the PPT cholinergic cell compartment. The aim of this study was to identify the role of GABA and its receptor...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2012
Alain Watts Howard J Gritton Jamie Sweigart Gina R Poe

Rapid eye movement (REM) sleep enhances hippocampus-dependent associative memory, but REM deprivation has little impact on striatum-dependent procedural learning. Antidepressant medications are known to inhibit REM sleep, but it is not well understood if antidepressant treatments impact learning and memory. We explored antidepressant REM suppression effects on learning by training animals daily...

2015
Florian Chouchou Jean-Marc Chauny Pierre Rainville Gilles J. Lavigne Andrej A. Romanovsky

The placebo effect is a neurobiological and psychophysiological process known to influence perceived pain relief. Optimization of placebo analgesia may contribute to the clinical efficacy and effectiveness of medication for acute and chronic pain management. We know that the placebo effect operates through two main mechanisms, expectations and learning, which is also influenced by sleep. Moreov...

2008
Yolanda del Río-Portilla Miguel Angel Guevara María Corsi-Cabrera

Correspondence: María Corsi-Cabrera, Sleep Laboratory, Facultad de Psicología, Posgrado, Universidad Nacional Autónoma de México, Av. Universidad 3004, México, D.F. 04510, México. Phone: (52-55)6-22-22-51; Fax: (52-55)6-22-23-10. [email protected] Abstract. Gamma EEG and MEG activity was studied immediately after REM sleep eye movement onset as an index of cortical activation. Two strateg...

2016
Fabrizio De Carli Paola Proserpio Elisa Morrone Ivana Sartori Michele Ferrara Steve Alex Gibbs Luigi De Gennaro Giorgio Lo Russo Lino Nobili

When dreaming during rapid eye movement (REM) sleep, we can perform complex motor behaviors while remaining motionless. How the motor cortex behaves during this state remains unknown. Here, using intracerebral electrodes sampling the human motor cortex in pharmacoresistant epileptic patients, we report a pattern of electroencephalographic activation during REM sleep similar to that observed dur...

Journal: :Annals of the New York Academy of Sciences 2017
Rubin Naiman

We are at least as dream deprived as we are sleep deprived. Many of the health concerns attributed to sleep loss result from a silent epidemic of REM sleep deprivation. REM/dream loss is an unrecognized public health hazard that silently wreaks havoc with our lives, contributing to illness, depression, and an erosion of consciousness. This paper compiles data about the causes and extent of REM/...

Journal: :Psychiatry research 1985
R H van den Hoofdakker D G Beersma

Sleep in depression is characterized by the occurrence of episodes of rapid eye movement (REM) sleep at sleep onset. The empirical foundations of three hypotheses about the origin of this phenomenon are examined: A circadian rhythm hypothesis stating that sleep onset REM episodes (SOREMs) are the result of an abnormal phase-position of the REM sleep production cycle. A REM sleep-slow wave sleep...

2000
Vincenzo Natale

S leep and dream psychophysiology has been dominated for many years and, under certain aspects still today, by strong bias which considered the dreamlike mental activity as a peculiar aspect of REM sleep. The discovery of the REM phase (1), which determined a change in sleep research, raised great expectations. Going by the results of the first experiments on REM sleep, Dement and Kleitmann (2)...

Journal: :Biophysical journal 2014
D Beqollari C F Romberg U Meza S Papadopoulos R A Bannister

Work in heterologous systems has revealed that members of the Rad, Rem, Rem2, Gem/Kir (RGK) family of small GTP-binding proteins profoundly inhibit L-type Ca(2+) channels via three mechanisms: 1), reduction of membrane expression; 2), immobilization of the voltage-sensors; and 3), reduction of Po without impaired voltage-sensor movement. However, the question of which mode is the critical one f...

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