HIGHLIGHTS Eucalyptus cinerea essential oil (EO) contains 1,8-cineole as the main component. This EO demonstrated antioxidant and antimicrobial properties. reduced viability of Jurkat Calu-3 cells decreased DNA content. had cell death mechanism related to apoptosis.

This study aimed to investigate whether Opuntia spp-extracts protect against diclofenac (DF)-induced hepatotoxicity. Rats were pretreated with extracts, betanin (Bet) and N-acetylcysteine (NAC) followed by a single challenge of diclofenac. Liver tissue was collected for biochemical histological analysis. Primary rat hepatocytes treated (400 µmol/L) without pretreatment extract. Apoptosis measur...