Background: The anatomy of small saphenous vein (SSV) is very variable because of its complex embryological origin. SSV incompetence often causes reflux that goes to the perforating veins, sometimes not respecting the anatomical course. Objective: To analyze differences in reflux direction and reentry in the SSV. Methods: In this prospective, observational study, 60 lower limbs with SSV incompe...

A dual-pathway theory to explain atrioventricular-nodal (AVN) reentry has been proposed previously. However, the exact anatomical and functional correlates of the fast pathway (FP) and slow pathway (SP) have not yet been elucidated. We used optical mapping to reconstruct patterns of activation during retrograde conduction through the AVN and during AVN reentry in the triangles of Koch of 12 rab...

Inclusion body myositis (IBM), a degenerative and inflammatory disorder of skeletal muscle, and Alzheimer's disease share protein derangements and attrition of postmitotic cells. Overexpression of cyclins and proliferating cell nuclear antigen (PCNA) and evidence for DNA replication is reported in Alzheimer's disease brain, possibly contributing to neuronal death. It is unknown whether aberrant...

AIMS Contemporary ionic-based membrane models are computationally expensive and are not intended to match the properties of a given experimental preparation. The aim of this work was to use measured restitution properties of electrically remodelled atrial tissue to develop a simplified membrane model based on the Fenton-Karma (FK) equations amenable to large-scale simulation of chronic atrial f...

Following the reentry of Intermediate eXperimental Vehicle in 2015, a lot efforts were carried out at ONERA for post-flight analysis and reconstruction heat flux applied to vehicle. This flight represents unique means validation computational tools employed design such mission. The aim this paper is exploit first time these data rarefied portion vehicle’s reentry. In context, DSMC simulations p...

Abstract Funding Acknowledgements Type of funding sources: None. Background Adenosine (ADN) infusion may terminate focal atrial tachycardia (AT). However, the effect ADN on reentrant (RAT) is unclear and based case reports small series. These latter included mostly patients with cavotricuspid isthmus-dependent flutter provided conflicting results, RAT termination found when it involved septal o...

BACKGROUND Approximately 600,000 persons are released from prison annually in the United States. Relatively few receive sufficient re-entry services and are at risk for unemployment, homelessness, poverty, substance abuse relapse and recidivism. Persons leaving prison who have a mental illness and/or a substance use disorder are particularly challenged. This project aims to create a peer mentor...

The presence of complex geometries and/or multiple bodies during atmospheric reentry may lead to and directional flow features, such as shock waves shear layers, that need be correctly predicted ensure accurate calculation the aerothermal loads reentry. Central in ensuring reliable numerical prediction is adoption meshes grid independence minimize misalignment between features cell interfaces, ...

We model electrical wave propagation in a ring of cardiac tissue using an mth-order difference equation, where m denotes the number of cells in the ring. Under physiologically reasonable assumptions, the difference equation has a unique equilibrium solution. Applying Jury's stability test, we prove a theorem concerning the local asymptotic stability of this equilibrium solution. Our results yie...