We examined faecal egg count reduction tests (FECRTs) conducted with hookworm-infected humans in Ghana in 2007 (study 1) and 2010 (study 2) in order to explore aspects of the test analysis. Some subjects showed increased FEC following drug treatment. This occurred mostly in <150 epg pre-treatment FEC subjects. We sought a means to remove 'erroneous' negative drug efficacy cases from the FECRT a...

Log-linear-binomial distribution was introduced for describing the behavior of the sum of dependent Bernoulli random variables. The distribution is a generalization of binomial distribution that allows construction of a broad class of distributions. In this paper, we consider the problem of estimating the two parameters of log-linearbinomial distribution by moment and maximum likelihood methods...

We discuss the identification of genes that are associated with an outcome in RNA sequencing and other sequence-based comparative genomic experiments. RNA-sequencing data take the form of counts, so models based on the Gaussian distribution are unsuitable. Moreover, normalization is challenging because different sequencing experiments may generate quite different total numbers of reads. To over...

Aim Red cell distribution width (RDW), an index of erythrocyte size, is associated with high risk for cardiovascular disease. Nondipping hypertension (HT) is lack of nocturnal fall in blood pressure(BP). The association between RDW and non-dipping BP in normotensive and hypertensive patients was investigated. Methods A total of 170 patients were categorized into 4 groups: Normotensive-Dipper (N...

This study compared social looking and response to novelty in preschool-aged children (47-68 mo) with or without iron deficiency anemia (IDA). Iron status of the participants from a low-income community in New Delhi, India, was based on venous hemoglobin, mean corpuscular volume, and red cell distribution width. Children's social looking toward adults, affect, and wary or hesitant behavior in r...

We consider a random network evolving in continuous time in which new nodes are born and old may die, and where undirected edges between nodes are created randomly and may also disappear. The node population is Markovian and so is the creation and deletion of edges, given the node population. Each node is equipped with a random social index and the intensity at which a node creates new edges is...

Methods for interval estimation of the ratio of two independent coefficients of variation (CVs) of the delta-lognormal distribution are proposed based on the concept of the generalized variable approach (GPA) and the method of variance estimates recovery (MOVER). The performances of both methods are assessed through Monte Carlo simulation in terms of the coverage probabilities and average lengths.

This paper presents estimations of the parameters included in linear exponential distribution, based on grouped and censored data. The methods of maximum likelihood, regression and Bayes are discussed. The maximum likelihood method does not provide closed forms for the estimations, thus numerical procedure is used. The regression estimates of the parameters are used as guess values to get the m...

AIM OF THE STUDY Data are available indicating that red blood cell distribution width (RDW) is higher in cancer patients compared to healthy individuals or benign events. In our study, we aimed to investigate the influence of different RDW levels on survival in lung cancer patients. MATERIAL AND METHODS Clinical and laboratory data from 146 patients with lung cancer and 40 healthy subjects we...

Methacholine provocation tests are aimed at determining bronchial responsiveness. Recent investigations stress the importance of considering the entire log-dose response curve, yielding not only the provocative dose producing a 20% change in forced expiratory volume in one second (FEV1) (PC20), but also the plateau value and the steepest slope of the curve (reactivity). In three control subject...