We describe a case of recurrent coccidioidal meningitis in which a fungal biofilm on the tip of ventriculo-peritoneal shunt tubing was likely responsible for a 4-year persistence of Coccidioides immitis, despite the patient's taking an adequate dosage of fluconazole. Fungal biofilms should be considered as a cause for treatment failure and fungal persistence, especially when artificial prosthes...

MR showed a neurenteric cyst posterior to the cervicomedullary junction in a man with chronic recurrent aseptic meningitis. On T1-weighted MR, the cyst was of high intensity in relation to the brain, and on T2-weighted MR it was of less intensity than cerebrospinal fluid.

Introduction Cryopyrin-associated periodic syndrome (CAPS) is a rare autoinflammatory disease. Generalized manifestations like recurrent fever and fatigue and organ disease like reduced vision, hearing loss, bone deformities and aseptic meningitis impair patients’ well-being. While most physical complaints are well defined and managed by effective IL-1 inhibition, areas of psychosocial needs ar...

Multiple cysts in both hemispheres were detected in four children under 1 year of age by real-time sonographic sector scanning. These cysts, typical of multiple cystic encephalomalacia, followed viral encephalitis in two, bacterial meningitis in one, and bacterial meningitis superimposed on intracerebral hemorrhage in one. The diagnosis of multiple cystic encephalomalacia, which has a grave pro...

modifying anti-rheumatic drug (DMARD) therapy in consultation with the British Association of Dermatologists. Rheumatology 2008;47:924–5. 3 University Hospital Birmingham NHS Foundation Trust. A–Z services: rheumatology. Guidelines for the management of rheumatology patients. http://www.uhb.nhs. uk/Services/Rheumatology/Information%20for%20Clinicians/Guidelines.aspx (24 June 2008, date last acc...

Pierre Mollaret described his first case of benign recurrent meningitis in 1928. About 50 years later, he wrote that nothing could be added to the original description and that the etiology remained to be discovered [1]. However, thanks to new technologies such as immu-noblotting and polymerase chain reaction (PCR) it is now sometimes possible to demonstrate the infectious origin of such syndro...