نتایج جستجو برای: rectal administration
تعداد نتایج: 263050 فیلتر نتایج به سال:
BACKGROUND & AIMS Basic fibroblast growth factor (bFGF) is a promising therapeutic agent for various diseases. It remains unclear, however, whether bFGF is effective for the treatment of inflammatory bowel disease. The aim of this study was to examine the efficacy of bFGF on 2 experimental murine colitis models and to investigate its molecular mechanisms. METHODS We evaluated the effects of h...
cancer pain. The oral route is the first choice in administering medication to relieve it, but clinical experience has shown that alternative routes of administration should be employed for patients suffering from nausea and vomiting. Furthermore, as morphine is subjected to the extensive first-pass metabolism after oral administration, the rectal administration of morphine, which can partially...
Probiotics have been advocated as a novel therapeutic approach to respiratory disease, but knowledge of how oral administration of probiotics influences the respiratory microbiota is needed. Using 16S rRNA amplicon sequencing of bacterial DNA our objective was to determine whether oral probiotics changed the composition of the upper and lower airway, rectal, and blood microbiota. We hypothesize...
background: in intracavitary brachytherapy for gynecological cancers, various techniques are used to locate the anterior rectal wall nearest to the sources but there is no consensus on the best method to do so. this study aimed to compare a technique used routinely in some centers that employs a wire marker to locate the position of the maximum rectal dose point, versus the method recommended b...
Rectal drug administration could offer advantages in the delivery of medicines for children by avoiding swallowability issues, improving stability and enabling caregivers. This study aimed to evaluate rectal bioavailability hollow-type suppositories (HTS) understand effect two chemical forms amoxicillin: amoxicillin sodium (AS) or trihydrate (AMT). HTS were prepared incorporating a lipophilic c...
Low-back pain is a common disease and a considerable economic burden in modern societies. Complementary and alternative therapies for assisting management of pain and disability are sought by a large number of patients. In the present work, the most common herbs used to manage Low-back pain in Iranian traditional medicine (Persian medicine) and current literature has been investigated.Chapters ...
Introduction: Evaluation and treatment of foreign bodies in rectum involves careful history and physical examination. The cases of forced introduction of the objects most commonly are , sexual assault , self – introduced for anal eroticism and accidental insertion. Case Report: We describe a case of a patient with rectal impaction following self administration of a plastic bottle for anal ...
BackgroundIdeal rescue treatments for acute treatment of seizure clusters should be easy to administer, so it is important assess user perceptions these treatments. Diazepam nasal spray designed have a rapid, noninvasive, and socially acceptable route administration. Patient caregiver (including care partner) responses surveys from phase 3 safety study diazepam are reported.MethodsThe enrolled ...
BACKGROUND Unacceptable adverse effects, contraindications to and/or ineffectiveness of World Health Organization step III "pain ladder" drugs causes needless suffering among a population of cancer patients. Successful management of severe cancer pain may require invasive treatment. However, a patient's refusal of an invasive procedure necessitates that clinicians consider alternative options. ...
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