statement of problem: in recent years, numerous reports have been presented in the literature, about gingival overgrowth induced by nifedipine- a calcium antagonist- prescribed for hypertension and certain types of angina. purpose: the purpose of the present study was to investigate the prevalence rate of nifedipine induced gingival hyperplasia in patients and its probable relationship with age...

AIM To study the serosal reaction in gastrectomy specimens with benign chronic peptic ulcers. METHODS Gastrectomy specimens were fixed in neutral buffered formalin and paraffin wax, and examined using immunohistochemical and ultrastructural techniques. RESULTS Nine of the 22 (41%) cases examined showed reactive hyperplasia of the serosal cells. The cells were predominantly spindle-shaped an...

Fallopian tube neoplasms are rare. We report a rare case of fallopian tube papilloma discovered incidentally in a 45 year old female, operated for procidentia. Right tube was dilated at the infundibular region, with friable grey white tissue in the lumen. Microscopy showed delicate branching papillae lined by a single layer of epithelium resembling tubal lining. There were no features to sugges...

Epithelioid hemangioma, also known as angiolymphoid hyperplasia with eosinophilia, is a cutaneous angioproliferative lesion that follows a benign clinical course. It is most frequently localized in the skin of the head and neck region; although it may sometimes arise deeper in soft tissues, orbital involvement is rare. Here we describe a patient who developed multiple epithelioid hemangiomas, i...

Pseudo-tumoral lesions of the cervix implies some reactive, non-neoplastic changes (metaplasia, hyperplasia, inflammation) that, occasionally, are wrong interpreted as precancerous or malign lesions. Even some can present architectural or cytological abnormal aspects, these are different from the one noted in carcinomas or the precursor lesions of carcinomas. Them recognition is indispensable i...

A 40-year-old heterosexual African man was admitted with fever, night sweats and lymphadenopathy. His human immunodeficiency virus antibody test was positive. Initial lymph node biopsy revealed reactive hyperplasia only. He was empirically treated for tuberculosis. However, symptoms persisted and a repeat lymph node biopsy was obtained, which confirmed Hodgkin's disease. This emphasises the nee...

BACKGROUND Abnormalities in the TP53 are regarded as the most consistent findings in oral squamous cell carcinoma. Two related members of the TP53 family, p73 and p63, have shown remarkable structural similarity to TP53, indicating possible functional and biological interactions. The aim of the present study was to investigate the expression of p63 protein and mRNA in oral epithelial dysplasia....

OBJECTIVE AND IMPORTANCE despite recent progress in imaging, it is still difficult to distinguish between pituitary adenoma and hyperplasia, even using Magnetic Resonance Imaging (MRI) with gadolinium injection. We describe an example of reactive pituitary hyperplasia from primary hypothyroidism that mimicked a pituitary macroadenoma in a child. CLINICAL PRESENTATION a 10 year old boy present...

PURPOSE Pleural nodular histiocytic/mesothelial hyperplasia is a nodular histiocytic/mesothelial proliferation, often delimiting cystic cavities, due to irritation by a pulmonary noxa. Case report results: The patient had right pleural parietal and diaphragmatic thickness, with pleural effusion, without lung alterations. He previously underwent left hemicolectomy and liver resection, due to a d...