This study investigated the effects of daily intraperitoneal injections of N-methyl-D-aspartate receptor antagonist MK-801 and nitric oxide synthase inhibitor nitro-L-arginine (L-NA) on the survival of retinal ganglion cells (RGCs) at 1 and 2 weeks after unilateral optic nerve transection in adult hamsters. The left optic nerves of all animals were transected intraorbitally 1 mm from the optic ...

Using first-principles calculations, we describe and compare atomistic lithiation, sodiation, and magnesiation processes in black phosphorous with a layered structure similar to graphite for Li-, Na-, and Mg-ion batteries because graphite is not considered to be an electrode material for Na- and Mg-ion batteries. The three processes are similar in that an intercalation mechanism occurs at low L...

Maximal activation of a Na+-dependent adenosine diphosphate-adenosine triphosphate exchange reaction mediated by kidney microsomes was achieved at 0.1 mu and 0.4 mu Mg++ in the presence of 1.5 mM and 32 mM Na+, respectively. K+ inhibited the Na+-dependent exchange rate when lower concentrations of Na+ and Mg++ were used and stimulated it in the presence of 0.4 mM Mg++ and 32 mM Na+. The inhibit...

High dietary sodium intake triggers increased blood pressure (BP). Animal studies show that dietary salt loading results in dermal Na+ accumulation and lymphangiogenesis mediated by VEGF-C (vascular endothelial growth factor C), both attenuating the rise in BP. Our objective was to determine whether these mechanisms function in humans. We assessed skin electrolytes, BP, and plasma VEGF-C in 48 ...

1 Methimazole (1-methyl-2-mercaptoimidazole, MMI) and propylthiouracil (6-propyl-2-thiouracil, PTU) which are used in the therapy of hyperthyroidism were found to reduce brain noradrenaline (NA) content. Endogenous NA levels in rat brain were reduced from 1 to 6 h after intraperitoneal injection of MMI by doses in excess of 25 mg/kg and by PTU at a dose of 50 mg/kg. However, endogenous NA in th...

ABSTRACT- Seed germination and early seedling growth are critical stages for plants establishment and production, particularly under salinity conditions. Exogenous application of silicon (Si) can enhance germination as well as seedling growth. In this experiment, the effect of priming with Si (0, 0.75, 1.5 and 2.25 mM sodium silicate) on seed germination and seedling growth under NaCl (0, 100 a...

Renal function was examined in adult rainbow trout (Oncorhynchus mykiss) after chronic exposure to a sublethal level of dietary Cd (500 mg/kg diet) for 52 d and during a subsequent challenge to waterborne Cd (10 microg/L) for 72 h. Dietary Cd had no major effects on UFR (urine flow rate) and GFR (glomerular filtration rate) but caused increased renal excretion of glucose, protein, and major ion...

This study was carried out in the Ravar plain, a typical arid zone in southeastern Iran, with the objectives of evaluating hydrochemical quality of the groundwater resources and identifying the processes that modify the groundwater composition. Groundwater samples were collected from representative wells spread over the study area. Major cations and anions along with physico-chemical parameters...