نتایج جستجو برای: rapid curriculum renewal
تعداد نتایج: 365112 فیلتر نتایج به سال:
The hypothalamus plays a crucial role in the control of the energy balance and also retains neurogenic potential into adulthood. Recent studies have reported the severe alteration of the cell turn-over in the hypothalamus of obese animals and it has been proposed that a neurogenic deficiency in the hypothalamus could be involved in the development of obesity. To explore this possibility, we exa...
Hematopoietic stem cells (HSCs) are rare residents of the bone marrow responsible for the lifelong production of blood cells. Regulation of the balance between HSC self-renewal and differentiation is central to hematopoiesis, allowing precisely regulated generation of mature blood cells at steady state and expanded production at times of rapid need, as well as maintaining ongoing stem cell capa...
The miR-294 and miR-302 microRNAs promote the abbreviated G1 phase of the embryonic stem cell (ESC) cell cycle and suppress differentiation induced by let-7. Here, we evaluated the role of the retinoblastoma (Rb) family proteins in these settings. Under normal growth conditions, miR-294 promoted the rapid G1-S transition independent of the Rb family. In contrast, miR-294 suppressed the further ...
Despite progress in developing defined conditions for human embryonic stem cell (hESC) cultures, little is known about the cell-surface receptors that are activated under conditions supportive of hESC self-renewal. A simultaneous interrogation of 42 receptor tyrosine kinases (RTKs) in hESCs following stimulation with mouse embryonic fibroblast (MEF) conditioned medium (CM) revealed rapid and pr...
Duchenne muscular dystrophy (DMD) is a devastating disease characterized by muscle wasting, loss of mobility and death in early adulthood. Satellite cells are muscle-resident stem cells responsible for the repair and regeneration of damaged muscles. One pathological feature of DMD is the progressive depletion of satellite cells, leading to the failure of muscle repair. Here, we attempted to exp...
In this paper, we construct fuzzy renewal processes involving fuzzy random variables. We first extend the renewal processes to the fuzzy renewal processes where interarrival times, rewards, and stopping times are all fuzzy random variables. According to these fuzzy renewal processes, we then extend some theorems of renewal processes to those in fuzzy renewal processes. These are elementary rene...
Embryonic stem (ES) cells fluctuate between self-renewal and the threshold of differentiation. Signalling via the fibroblast growth factor (Fgf)/Erk pathway is required to progress from this dynamic state and promote mouse ES cell differentiation. Retinoic acid also induces differentiation in many cellular contexts, but its mechanism of action in relation to Fgf/Erk signalling in ES cells is po...
the main purpose of this research is design a competency model for curriculum planners. analysis - inductively method with of the curriculum planner’s expert’s viewpoint was used. to determine the competency model for curriculum planner’s 5-stage methodology byham & moyer was used. in the first phase was reviewed subject literature and academic resources. curriculum experts were interviewed in ...
Torula yeast is the most common bait used by growers and agriculture professionals for trapping of tephritid flies in Dominican Republic. However, efficiency influenced weather conditions, aging, contamination with undesirable microorganisms. Thus, additives such as benzalkonium chloride, a quaternary ammonium compound, have been together torula stabilizer. This study evaluated effect addition ...
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