In this paper, we describe a resource assignment problem (RAP) for a large-scale computing utility, such as an Internet data center. The problem is defined as follows: For a given topology of a network consisting of switches and servers with varying capabilities, and for a given application with a distributed architecture, decide which server from the physical network should be assigned to each...

BACKGROUND The applicability of microarray-based transcriptome massive analysis is often limited by the need for large amounts of high-quality RNA. RNA arbitrarily primed PCR (RAP-PCR) is an unbiased fingerprinting PCR technique that reduces both the amount of initial material needed and the complexity of the transcriptome. The aim of this study was to evaluate the feasibility of using hybridiz...

The application of recycled asphalt pavement (RAP) on a large scale is highly promoted to meet the current needs carbon neutrality and sustainable development purposes. However, majority RAP mixture productions are currently relying restoring effects provided by rejuvenators. Therefore, study focuses feasibility using high penetration binder (HPAB) in as replacement for conventional In this stu...

In clinical cardiac tamponade, open-catheter intrapericardial pressure (IPP) may be used to estimate left ventricular transmural filling pressure (TMFP). However, it has been suggested recently that right atrial pressure (RAP) is superior to IPP in assessing true extracardiac pressure during pericardial drainage. In 10 patients with subacute cardiac tamponade, pulmonary wedge pressure (PWP), RA...

family GTPases [2, 3], in a screen for PtdIns(3,4,5)P3 Rap Binds to ARAP3 and Activates Its Rho binding proteins. PtdIns(3,4,5)P3 is the lipid product of GAP Activity In Vitro class I phosphoinositide 3OH-kinases (PI3Ks) [4] and Just C-terminal to ARAP3’s Rho GAP domain lies a is a signaling molecule used by growth factor recepweakly conserved Ras binding domain (RBD; Figure 2A). tors and integ...

PURPOSE To evaluate the short-term efficacy and safety of intravitreal bevacizumab injection (IVBI) in patients with retinal angiomatous proliferation (RAP). METHODS Seven eyes of 5 patients with RAP were included in this study. All of the eyes evidenced stage 2 RAP lesions, except for one eye with a stage 3 lesion. IVBI (1.25 mg/0.05 cc) were conducted at 4 or 6-week intervals. Complete ocul...

Traditional LCA of central plant hot recycling shows that, the higher RAP added, the less energy consumed. This conclusion is mainly based on the calculation of reduced raw material. However, when the content of Reclaimed asphalt pavement mixture (RAP) reaches some level, it is needed to take measures such as using additive or improved construction method for maintain the performance of asphalt...

BACKGROUND Autophagy is a biological process during which cells digest organelles in their cytoplasm and recycle the constituents. The impact of autophagy in the heart, however, remains unclear in part because of the inability to noninvasively image this process in living animals. METHODS AND RESULTS Here, we report the use of fluorescence molecular tomography and a cathepsin-activatable fluo...

N-RAP is an actin binding LIM protein expressed in skeletal and cardiac muscle tissues (Luo et al., 1997). In adult mice, N-RAP is found at the longitudinal ends of striated muscles at sites of mechanical coupling between the myofibrils and the cell membrane (Luo et al., 1997). These regions are the myotendinous junctions in skeletal muscle and the intercalated disks in heart muscle, and ultras...

Homicide is a rare event, but depictions of it are quite common in our culture and discourse. Commercially successful rappers have appropriated homicide as a central theme in their lyrical compositions. The tremendous success of rap music is indicative of its increasing popular appeal and cultural impact. We reveal the ways homicide is constructed within rap music and its frequency of occurrenc...