Cholesterol dissolved in sesame oil and injected regularly for a period of from 7 to 8 months into the jugular vein of four young dogs has caused in each animal larger and smaller nodules protruding to some degree into the lumen of the pulmonary artery and also here and there some diffuse thickenings, the whole closely resembling human arteriosclerosis. These changes commence at the origin of t...

Diffraction of a normal shock wave has been the subject of numerous studies, dating back work of Whitham [1]. A large number of the complex flow features present were highlighted in the well known work by Skews [2]. Fig. 1 shows the flow features behind a strong shock diffracting around a sharp corner. Skews showed that for angles greater than 75o the flow features become independent of the cor...

A new method has been described for the study in vivo of thrombus formation in blood circulating extracorporeally in an artificial loop. This method permits of control of many factors, and hence of intensive study of thrombus formation under many and varied conditions. It admits of separate study of the formation of white thrombi and of the deposition of fibrin, which may apparently be independ...

The hormone, melatonin is produced with circadian rhythm by the pineal gland in humans. The melatonin rhythm provides an endogenous synchronizer, modulating e.g. blood pressure, body temperature, cortisol rhythm, sleep-awake-cycle, immune function and anti-oxidative defence. Interestingly, a number of experimental animal studies demonstrate significant dose-dependent anti-nociceptive effects of...

background: low dose theophylline may have some anti-inflammatory effects on copd patients. this study was conducted to determine the effect of oral low dose theophylline on serum crp level in patients with stable copd. methods: in this double blind randomized clinical trail study, 50 patients (25 in experimental and 25 in placebo group) were enrolled into the study by randomized blocking metho...

Background: This systematic review and meta-analysis examines how pulmonary rehabilitation impacts in patients suffering from subacute long COVID-19 infections, gauging enhancements of dyspnea, physical function, quality life, psychological state (anxiety depression), fatigue. Methods: Three electronic databases (PubMed, Web Science, Cochrane Library) were systematically searched for full-text ...