We have developed a superresolution vibrational imaging method by simultaneous detection of Raman and hyper-Raman scattering. Raman and hyper-Raman images obtained with the same laser spot carry independent information on the sample spatial distribution, owing to different signal dependence (linear in Raman and quadratic in hyper-Raman) on the incident light intensity. This information can be q...

Raman spectroscopy is a label-free method of obtaining detailed chemical information about samples. Its compatibility with living tissue makes it an attractive choice for biomedical analysis, yet its translation from a research tool to a clinical tool has been slow, hampered by fundamental Raman scattering issues such as long integration times and limited penetration depth. In this review we de...

We have performed Raman spectroscopy using a near-field scanning optical microscope. This avoids the diffraction limit inherent with conventional optical microscopy techniques involving far-field optical components, and allows volumes significantly smaller than the cube of the wavelength to be investigated. The small sample volume coupled with the light-starved nature of the Raman effect itself...

Microalgae are extensively researched as potential feedstocks for biofuel production. Energy-rich compounds in microalgae, such as lipids, require efficient characterization techniques to investigate the metabolic pathways and the environmental factors influencing their accumulation. The model green alga Coccomyxa accumulates significant amounts of triacylglycerols (TAGs) under nitrogen depleti...

Bioactive materials including glass and glass-ceramics are nowadays used as medical implants for orthopedic applications. In this study several samples of glass-ceramics have been prepared using both heat treatment and sol-gel processes. The structure and bioactivity of these samples based on their interaction with simulated body fluid (SBF) have been determined. In-vitor, using the Raman s...

Surface-enhanced Raman spectroscopy (SERS) and femtosecond stimulated Raman spectroscopy (FSRS) have revolutionized the Raman spectroscopy field. SERS provides spectroscopic detection of single molecules, and FSRS enables the acquisition of Raman spectra on the ultrafast time scale of molecular motion. Here, we present the first successful combination of these two techniques, demonstrating surf...

The intensity ratio between two major Raman bands in graphene is one of the most important information for physics of graphene and has been believed to represent various intrinsic properties of graphene without critical assessment of extrinsic effects. We report a micro Raman spectroscopy study on the Raman intensity ratio of the 2D band to the G Raman band of graphene varying the thickness of ...

Fast and sensitive Raman spectroscopy measurements are imperative for a large number of applications in biomedical imaging, remote sensing and material characterization. Stimulated Raman spectroscopy offers a substantial improvement in the signal-to-noise ratio but is often limited to a discrete number of wavelengths. In this report, by introducing an electronically-tunable acousto-optical filt...

Introduction Raman spectroscopy is one of the most common techniques for materials identification and characterization. Based on inelastic scattering of a monochromatic excitation source, Raman measures vibrational, rotational and other low-frequency modes in a system. It’s not only characteristic for functional groups, but also sensitive to backbone and crystalline structures. Therefore, Raman...

We have carried out absolute calibrations of the LHD YAG Thomson scattering system by using Raman scattering and Rayleigh scattering in order to verify the applicability of Rayleigh calibration in the LHD Thomson scattering, and make a comparative study of Raman and Rayleigh calibrations. In the LHD Thomson scattering device, Rayleigh calibration is expected to give more reliable calibration fa...