Salmonella typhimurium LT-2 was compared with radioresistant (B/r) and radiosensitive (B(s-2)) strains of Escherichia coli in respect to the survival, deoxyribonucleic acid (DNA) breakdown, and DNA synthesis after X irradiation. It is shown that S. typhimurium LT-2 is about four times more sensitive than E. coli B/r but less sensitive than B(s-2). The DNA breakdown is in S. typhimurium LT-2 low...

BACKGROUND The most common long-term complication of radiation therapy (RT) for head and neck cancer is dry mouth or xerostomia. Salivary glands are radiosensitive; their destruction begins shortly after the initiation of therapy with the extent of injury directly related to the amount of radiation to which they are exposed. The subsequent xerostomia is challenging to manage, leads to multiple ...

The effect of external gamma-irradiation on the survival of alveolar macrophages (AM) and on the extracellular release of 59Fe from AM-ingested [59Fe]iron hydroxide colloid was investigated in vitro using cells from C3H mice and Wistar rats. 59Fe release from mouse AM was enhanced by irradiation in a dose-dependent fashion, but irradiation up to 112 Gy did not affect the release from rat AM. Ce...

Pain treatment due to cancer is a large fraction of the care in a radiotherapy department. While radiation treatment is very effective in reducing pain, the pathophysiology of bone metastases remains very complex. Reducing the number of tumour cells by radiation will reduce the pressure in bone marrow, but the very rapid response to radiation treatment seen in some patients is probably related ...

Four cases of adenoid cystic carcinoma (cylindroma) of accessory salivary tissue are described, and the diagnostic difficulties experienced are emphasized. The tumour infiltrates cranial and other nerves and may invade the central nervous system by this route. It is highly malignant and may metastasize widely both by haematogenous and lymphatic pathways. The tumour is radiosensitive and it is s...

Despite considerable research over the past three decades, the factors that control the response of human tumors to radiation remain poorly understood. Normal human cell strains studied in vitro show a rather narrow range in radiosensitivity (1), whereas human tumor cells vary considerably in their sensitivity to the cytotoxic effects of radiation (2,3). Cells from some types of tumors such as ...

Cultures of Salmonella subjected to repeated cycles of gamma-irradiation and subculture developed radiation resistance sooner at a low cycling dose ( approximately 1% survival) compared to a high cycling dose ( approximately 0.001% survival). Radioresistant cells in a population of radiosensitive cells of Salmonella newport or S. typhimurium could be selected by the double-irradiation plate met...

introduction: plasmacytoma is a monoclonal proliferation of plasma cells. it can be an isolated lesion, for which the term extramedullary plasmacytoma is used, or a representation of multiple myeloma.the upper respiratory tract is the most common site for an extramedullary plasmacytoma. sinonasal plasmacytomas cause different symptoms depending on the sites of origins and the areas of involveme...