Fifteen dogs were referred because of a spontaneous bone tumor, lameness, and local pain. The osteosarcoma diagnosis was established by clinical examination, X-ray, bone scintigraphy, and histological examination of biopsy material. The tumors were located in the extremities (n = 12), scapula (n = 1), maxilla (n = 1), and the frontal bone (n = 1). The dogs were given one to four i.v. injections...

BACKGROUND Bony metastases were occasionally the initial presentations of malignancy. Overlooking of bony changes on radiographs in cancer patients with non-specific clinical symptoms may lead to delayed diagnosis. CASE PRESENTATION We presented a 70-year-old male having hypercalcemia and diffuse osteoblastic bone metastases on routine plain films. Finally, prostate cancer was diagnosed with ...

UNLABELLED Biodistribution and dosimetry of 88Y (and equimolar 90Y) Janus-dodecanetetraacetic acid (DOTA) were performed using a three-step pretargeting protocol in BALB/c mice bearing mouse mammary adenocarcinoma (KHJJ) implants. Pretargeting was performed with mouse monoclonal antibody (mAb) 2D12.5 specific for yttrium-DOTA, and the chase was Y-DOTA-human transferrin conjugate. In this articl...

Although encouraging results have been obtained using systemic radioimmunotherapy in the treatment of cancer, it is likely that regional applications may prove more effective. One such strategy is the treatment of central nervous system leukemia in children by intrathecal instillation of targeting or nontargeting /.<particle emitting radionuclide carriers. The 11particle dosimetry of the spine ...

Conversion coefficients were calculated for fluence-to-absorbed dose, fluence-to-equivalent dose, fluence-to-effective dose and fluence-to-gray equivalent for isotropic exposure of an adult female and an adult male to tritons ((3)H(+)) in the energy range of 10 MeV to 1 TeV (0.01-1000 GeV). Coefficients were calculated using Monte Carlo transport code MCNPX 2.7.C and BodyBuilder™ 1.3 anthropomo...

Patients with metastatic differentiated thyroid cancer (DTC) may be prepared using either thyroid-stimulating hormone withdrawal (THW) or recombinant human thyroid-stimulating hormone (rhTSH) injections before 131I administration for treatment. The objective of this study was to compare the absorbed dose to the critical organs and tumors determined by 124I PET/CT-based dosimetry for 131I therap...

Abstract Targeted radionuclide therapy (TRT) and brachytherapy with alpha particles has gained significant clinical relevance recently. Absorbed dose traceability to a standard is currently lacking in the dosimetry chain. The short range of water &lt;100 μm complicates absorbed measurements form attenuation perturbation effects. aim this work was develop validate for from alpha-particle-emittin...

Radiation dose assessment in advanced synchrotron radiation facility is challenging due to the complexity and uncertainties of radiation source terms induced by high energy particle accelerator. Shanghai Synchrotron Radiation Facility (SSRF) is the first third-generation synchrotron facility in China, which was completed in 2009. Radiation dose assessment for workers at SSRF Beam lines is highl...