OBJECTIVE The aim of this study was to evaluate the usefulness of ROLL technique (Radioguided Occult Lesion Localization) as a verification method of suspicious lesions not related to breast disease found in PET-CT studies. MATERIAL AND METHODS We retrospectively evaluated 9 patients diagnosed of cancer or with suspected tumor disease who showed hypermetabolic lymph nodes in (18)F-FDG PET-CT....

BACKGROUND The radioguided localization of occult breast lesions (ROLL) technique often utilizes iodinated radiographic contrast to assure that the local injection of (99m)Tc-MAA corresponds to the location of the lesion under investigation. However, for this application, this contrast has several shortcomings. The objective of this study was to evaluate the safety, effectiveness and technical ...

Large-scale, controlled trials in the 1970s and 1980s demonstrated that wide resection (for example, quadrantectomy) was as effective as mastectomy for the treatment of breast cancer up to 3 cm in maximum diameter. Conservative treatment may also be extended to larger cancers following pre-operative chemotherapy to reduce tumor mass and leave sufficiently wide resection margins to ensure oncolo...

BACKGROUND The main prognostic factor in early staged breast cancer is the axillary lymph node metastatic affection. Sentinel lymph node biopsy, as a staging modality, significantly decreases surgical morbidity. The status of internal mammary lymph nodes gains an increased predictive role in grading breast carcinomas and modulation of postoperative therapeutic protocols. If positive, almost alw...

1Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy; 2Institute of Clinical Physiology, National Research Council, Pisa, Italy; 3Division of Surgical Oncology, National Cancer Institute, Genoa, Italy; 4Division of Surgical Oncology, Department of Oncology, Biology and Genetics, University of Genoa and National Cancer Institute, Genoa, Italy; 5Nuclear Medicine Se...

Mammography screening programs are frequently used for the detection of non-palpable clinically occult breast lesions and the widespread use of high-resolution ultrasound has increased the number of detected masses. Although most of the detected masses are benign and do not require surgery, sometimes surgery is needed because of discordance between results of pathologic and radiologic examinati...

Osteitis fibrosa cystica is the classic patognomonic form of skeletal disease in hyperparathyroidism that characterizes with decreased cortical bone thickness compared to increased cancellous bone. We present a case of 52-year old female patient with osteolysis of the left calf on radiographic images. The bone scan detected multiple focal pathological accumulations in the skull, left tibia, bot...